Publications of the emeritus-department "Neuroimmunology"
Journal Article (381)
2023
Journal Article
120 (30), e2302697120 (2023)
Visualizing the activation of encephalitogenic T cells in the ileal lamina propria by in vivo two-photon imaging. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
26 (11), 108143 (2023)
Oral vancomycin treatment suppresses gut trypsin activity and preserves intestinal barrier function during EAE. iScience
Journal Article
75 (5), pp. 748 - 759 (2023)
Activation of a latent epitope causing differential binding of anti-neutrophil cytoplasmic antibodies to proteinase 3. Arthritis and Rheumatology
Journal Article
299 (4), 103072 (2023)
Constitutive and induced forms of membrane-bound proteinase 3 interact with antineutrophil cytoplasmic antibodies and promote immune activation of neutrophils. The Journal of Biological Chemistry
Journal Article
20, 291 (2023)
An engineered Fc fusion protein that targets antigen-specific T cells and autoantibodies mitigates autoimmune disease. Journal of Neuroinflammation
Journal Article
15 (6), 1866 (2023)
Non-oncogene addiction of KRAS-mutant cancers to IL-1beta via versican and mononuclear IKKbeta. Cancers / Molecular Diversity Preservation International (MDPI)
Journal Article
120 (47), e2300733120 (2023)
A B cell–driven EAE mouse model reveals the impact of B cell-derived cytokines on CNS autoimmunity. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
15 (3), pp. 451 - 459 (2023)
Lactobacillus johnsonii BFE6154 ameliorates diet-induced hypercholesterolemia. Probiotics and Antimicrobial Proteins 2022
Journal Article
132 (23), e160089 (2022)
Protective alpha1-antitrypsin effects in autoimmune vasculitis are compromised by methionine oxidation. The Journal of Clinical Investigation
Journal Article
219 (10), e20220759 (2022)
Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing. The Journal of experimental medicine
Journal Article
132 (1), pp. 562 - 570 (2022)
Two putative probiotic strains improve diet-induced hypercholesterolemia through modulating intestinal cholesterol uptake and hepatic cholesterol efflux. Journal of Applied Microbiology 2021
Journal Article
57 (5), 2001416 (2021)
Cathepsin B promotes collagen biosynthesis, which drives bronchiolitis obliterans syndrome. European Respiratory Journal
Journal Article
81 (13), pp. 3568 - 3579 (2021)
TIMP1 triggers neutrophil extracellular trap formation in pancreatic cancer. Cancer Research
Journal Article
57 (4), 2003755 (2021)
Proteinase release from activated neutrophils in mechanically ventilated patients with non-COVID-19 and COVID-19 pneumonia. European Respiratory Journal 2020
Journal Article
17 (1), 79 (2020)
Perturbation of gut microbiota decreases susceptibility but does not modulate ongoing autoimmune neurological disease. Journal of Neuroinflammation
Journal Article
63 (22), pp. 13258 - 13265 (2020)
Lung protection by cathepsin C inhibition: A new hope for COVID-19 and ARDS? Journal of Medicinal Chemistry 2019
Journal Article
49 (4), pp. 521 - 522 (2019)
Avraham Ben-Nun - Pioneer, fighter, friend. European Journal of Immunology
Journal Article
20 (6), 1433 (2019)
The genetic background of mice influences the effects of cigarette smoke on onset and severity of experimental autoimmune encephalomyelitis. International Journal of Molecular Sciences
Journal Article
49 (3), pp. 500 - 503 (2019)
BReDi mouse: A novel transgenic mouse strain to track and deplete Bcells. European Journal of Immunology
Journal Article
116 (30), pp. 14788 - 14790 (2019)
Autoimmune diabetes mellitus and the leaky gut. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
13 (9), pp. 1173 - 1185 (2019)
Microbial colonization in adulthood shapes the intestinal macrophage compartment. Journal of Crohn's and Colitis
Journal Article
142, pp. 838 - 840 (2019)
Secondary progressive multiple sclerosis and the gut-brain axis. Brain 2018
Journal Article
8, 10431 (2018)
Dietary non-fermentable fiber prevents autoimmune neurological disease by changing gut metabolic and immune status. Scientific Reports
Journal Article
61 (5), pp. 1858 - 1870 (2018)
Exploiting the S4-S5 specificity of human neutrophil proteinase 3 to improve the potency of deptidyl Di(chlorophenyl)-phosphonate ester inhibitors: A kinetic and molecular modeling analysis. Journal of Medicinal Chemistry
Journal Article
293 (32), pp. 12415 - 12428 (2018)
Consequences of cathepsin C inactivation for membrane exposure of proteinase 3, the target antigen in autoimmune vasculitis. The Journal of Biological Chemistry
Journal Article
84 (2), pp. 315 - 328 (2018)
Pathogenicity of human antibodies against myelin oligodendrocyte glycoprotein. Annals of Neurology
Journal Article
557 (7707), pp. 642 - 643 (2018)
Gut molecules control brain inflammation. Nature
Journal Article
6 (3), pp. 370 - 388.e3 (2018)
Increased pancreatic protease activity in response to antibiotics impairs gut barrier and triggers colitis. Cellular and Molecular Gastroenterology and Hepatology
Journal Article
8, 16775 (2018)
Small molecule antagonists of NAADP-induced Ca2+ release in T-lymphocytes suggest potential therapeutic agents for autoimmune disease. Scientific Reports 2017
Journal Article
114 (40), pp. 10719 - 10724 (2017)
Gut microbiota from multiple sclerosis patients enables spontaneous autoimmune encephalomyelitis in mice. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
8, 406 (2017)
A novel cervical spinal cord window preparation allows for two-photon imaging of t-cell interactions with the cervical spinal cord microvasculature during experimental autoimmune encephalomyelitis. Frontiers in immunology
Journal Article
114 (31), pp. E6381 - E6389 (2017)
Visualizing context-dependent calcium signaling in encephalitogenic T cells in vivo by two-photon microscopy. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
26 (8), pp. 1522 - 1534 (2017)
DNMT1 mutations found in HSANIE patients affect interaction with UHRF1 and neuronal differentiation. Human Molecular Genetics
Journal Article
38 (7), pp. 483 - 497 (2017)
Brain Autoimmunity and Intestinal Microbiota: 100 Trillion Game Changers. Trends in Immunology
Journal Article
50 (1), pp. 57 - 60 (2017)
B cells in multiple sclerosis. Autoimmunity
Journal Article
136 (Suppl. 201), pp. 22 - 25 (2017)
Nature, nurture, and microbes: The development of multiple sclerosis. Acta Neurologica Scandinavica 2016
Journal Article
113 (28), pp. 7864 - 7869 (2016)
Distinct oligoclonal band antibodies in multiple sclerosis recognize ubiquitous self-proteins. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
6, 35413 (2016)
Quantitative analysis of protease recognition by inhibitors in plasma using microscale thermophoresis. Scientific Reports
Journal Article
15 (2), pp. 198 - 209 (2016)
The search for the target antigens of multiple sclerosis, part 1: Autoreactive CD4+T lymphocytes as pathogenic effectors and therapeutic targets. Lancet Neurology
Journal Article
15 (3), pp. 317 - 331 (2016)
The search for the target antigens of multiple sclerosis, part 2: CD8+T cells, B cells, and antibodies in the focus of reverse-translational research. Lancet Neurology
Journal Article
65 (3), pp. 235 - 242 (2016)
In vivo imaging in autoimmune diseases in the central nervous system. Allergology International
Journal Article
68 (3), pp. 603 - 630 (2016)
Inhibitors and antibody fragments as potential anti-inflammatory therapeutics targeting neutrophil proteinase 3 in human disease. Pharmacological Reviews
Journal Article
7, 451 (2016)
Tertiary lymphoid organs in central nervous system autoimmunity. Frontiers in immunology
Journal Article
55, pp. 68 - 75 (2016)
The gut-brain connection: Triggering of brain autoimmune disease by commensal gut bacteria. Rheumatology 2015
Journal Article
46 (1), pp. 197 - 202 (2015)
Deficiency of the stroke relevant HDAC9 gene attenuates atherosclerosis in accord with allele-specific effects at 7p21.1. Stroke
Journal Article
2 (4), e107 (2015)
αβ T-cell receptors from multiple sclerosis brain lesions show MAIT cell-related features. Neurology Neuroimmunology & Neuroinflammation
Journal Article
194 (2), pp. 542 - 552 (2015)
The immunoregulator soluble TACI is released by ADAM10 and reflects B cell activation in autoimmunity. Journal of Immunology
Journal Article
86 (8), pp. 925 - 933 (2015)
Multiple sclerosis and microbiota. From genome to metagenome? Nervenarzt
Journal Article
6, 7333 (2015)
γ-secretase directly sheds the survival receptor BCMA from plasma cells. Nature Communications
Journal Article
44 (4, Part 2), pp. e103 - e112 (2015)
The autoimmune concept of multiple sclerosis. Presse médicale & Quarterly medical review. Special Issue: Multiple sclerosis