Journal Article (381)

2002
Journal Article
Ziemssen, T.; Kümpfel, T.; Klinkert, W. E. F.; Neuhaus, O.; Hohlfeld, R.: Glatiramer acetate-specific T-helper 1-and 2-type cell lines produce BDNF: Implications for multiple sclerosis therapy. Brain 125, pp. 2381 - 2391 (2002)
Journal Article
Ziemssen, T.; Neuhaus, O.; Farina, C.; Hartung, H. P.; Hohlfeld, R.: Treatment of multiple sclerosis with glatiramer acetate - new information about its mechanisms of action, pharmacokinetics, adverse effects and clinical studies. Nervenarzt 73 (4), pp. 321 - 331 (2002)
Journal Article
Ziemssen, T.; Neuhaus, O.; Hohlfeld, R.: Risk-benefit assessment of glatiramer acetate in multiple sclerosis. Drug Safety 24 (13), pp. 979 - 990 (2002)
2001
Journal Article
Daubenberger, C. A.; Nickel, B.; Hübner, B.; Siegler, U.; Meinl, E.; Pluschke, G.: Herpesvirus saimiri transformed T cells and peripheral blood mononuclear cells restimulate identical antigen-specific human T cell clones. Journal of Immunological Methods 254 (1-2), pp. 99 - 108 (2001)
Journal Article
Egg, R.; Reindl, M.; Deisenhammer, F.; Linington, C.; Berger, T.: Anti-MOG and anti-MBP antibody subclasses in multiple sclerosis. Multiple Sclerosis Journal 7 (5), pp. 285 - 289 (2001)
Journal Article
Farina, C.; Bergh, F. T.; Albrecht, H.; Meinl, E.; Yassouridis, A.; Neuhaus, O.; Hohlfeld, R.: Treatment of multiple sclerosis with Copaxone (COP) Elispot assay detects COP-induced interleukin-4 and interferon-gamma response in blood cells. Brain 124, pp. 705 - 719 (2001)
Journal Article
Flügel, A.; Bradl, M.; Kreutzberg, G. W.; Graeber, M. B.: Transformation of donor-derived bone marrow precursors into host microglia during autoimmune CNS inflammation and during the retrograde response to axotomy. Journal of Neuroscience Research 66 (1), pp. 74 - 82 (2001)
Journal Article
Flugel, A.; Matsumuro, K.; Neumann, H.; Klinkert, W. E. F.; Birnbacher, R.; Lassmann, H.; Otten, U.; Wekerle, H.: Anti-inflammatory activity of nerve growth factor in experimental autoimmune encephalomyelitis: Inhibition of monocyte transendothelial migration. European Journal of Immunology 31 (1), pp. 11 - 22 (2001)
Journal Article
Hackstein, H.; Bitsch, A.; Bohnert, A.; Hofmann, H.; Weber, F.; Ohly, A.; Linington, C.; Maurer, M.; Poser, S.; Rieckmam, P. et al.; Bein, G.: Analysis of interleukin-4 receptor α chain variants in multiple sclerosis. Journal of Neuroimmunology 113 (2), pp. 240 - 248 (2001)
Journal Article
Iglesias, A.; Bauer, J.; Litzenburger, T.; Schubart, A.; Linington, C.: T- and B-cell responses to myelin oligodendrocyte glycoprotein in experimental autoimmune encephalomyelitis and multiple sclerosis. Glia 36 (2), pp. 220 - 234 (2001)
Journal Article
Medana, I.; Martinic, M. A.; Wekerle, H.; Neumann, H.: Transection of major histocompatibility complex class I-induced neurites by cytotoxic T lymphocytes. American Journal of Pathology 159 (3), pp. 809 - 815 (2001)
Journal Article
Meinl, E.; Derfuss, T.; Pirzer, R.; Blank, N.; Lengenfelder, D.; Blancher, A.; Le Deist, F.; Fleckenstein, B.; Hivroz, C.: Herpesvirus saimiri replaces ZAP-70 for CD3- and CD2-mediated T cell activation. The Journal of Biological Chemistry 276 (40), pp. 36902 - 36908 (2001)
Journal Article
Wiegers, G. J.; Stec, I. E. M.; Klinkert, W. E. F.; Linthorst, A. C. E.; Reul, J.: Bidirectional effects of corticosterone on splenic T-cell activation: Critical role of cell density and culture time. Neuroendocrinology 73 (2), pp. 139 - 148 (2001)
2000
Journal Article
Hohlfeld, R.; Kerschensteiner, M.; Stadelmann, C.; Lassmann, H.; Wekerle, H.: The neuroprotective effect of inflammation: Implications for the therapy of multiple sclerosis. Journal of Neuroimmunology 107 (2), pp. 161 - 166 (2000)
Journal Article
Meinl, E.; Hohlfeld, R.: T cell transformation with Herpesvirus saimiri: A tool for neuroimmunological research. Journal of Neuroimmunology 103 (1), pp. 1 - 7 (2000)
Journal Article
Stefferl, A.; Schubart, A.; Storch, M.; Amini, A.; Mather, I.; Lassmann, H.; Linington, C.: Butyrophilin, a milk protein, modulates the encephalitogenic T cell response to myelin oligodendrocyte glycoprotein in experimental autoimmune encephalomyelitis. The Journal of Immunology 165 (5), pp. 2859 - 2865 (2000)
1999
Journal Article
Bradl, M.; Bauer, J.; Inomata, T.; Zielasek, J.; Nave, K. A.; Toyka, K.; Lassmann, H.; Wekerle, H.: Transgenic Lewis rats overexpressing the proteolipid protein gene: Myelin degeneration and its effect on T cell-mediated experimental autoimmune encephalomyelitis. Acta Neuropathologica 97 (6), pp. 595 - 606 (1999)
Journal Article
Haase, C. G.; Faustmann, P. M.; Diener, H. C.: Acute disseminated encephalomyelitis (ADEM). Aktuelle Neurologie 26 (2), pp. 68 - 71 (1999)
Journal Article
Haase, C. G.; Hohlfeld, R.: Knochenmark- und Stammzelltransplantation bei multipler Sklerose? Nervenarzt 70 (2), pp. 178 - 181 (1999)
Journal Article
Hohlfeld, R.: Therapeutic strategies in multiple sclerosis. I. Immunotherapy. Philosophical Transactions of the Royal Society of London, Series B: Biological Sciences 354 (1390), pp. 1697 - 1710 (1999)
Journal Article
Kerschensteiner, M.; Gallmeier, E.; Behrens, L.; Vargas-Leal, V.; Misgeld, T.; Klinkert, W. E. F.; Kolbeck, R.; Hoppe, E.; Oropeza-Wekerle, R. L.; Bartke, I. et al.; Stadelmann, C.; Lassmann, H.; Wekerle, H.; Hohlfeld, R.: Activated human T cells, B cells, and monocytes produce brain-derived neurotrophic factor in vitro and in inflammatory brain lesions: A neuroprotective role of inflammation? Journal of Experimental Medicine 189 (5), pp. 865 - 870 (1999)
Journal Article
Reindl, M.; Linington, C.; Brehm, U.; Egg, R.; Dilitz, E.; Deisenhammer, F.; Poewe, W.; Berger, T.: Antibodies against the myelin oligodendrocyte glycoprotein and the myelin basic protein in multiple sclerosis and other neurological diseases: A comparative study. Brain 122, pp. 2047 - 2056 (1999)
Journal Article
Wiendl, H.; Neuhaus, O.; Stefan, H.: Treatment of Rasmussen's encephalitis. Deutsche Medizinische Wochenschrift 124 (31-32), pp. 937 - 939 (1999)
Journal Article
Wilharm, E.; Tschopp, J.; Jenne, D. E.: Biological activities of granzyme K are conserved in the mouse and account for residual Z-Lys-SBzl activity in granzyme A-deficient mice. FEBS Letters 459 (1), pp. 139 - 142 (1999)
1998
Journal Article
Bauer, J.; Bradl, M.; Hickey, W. F.; Forss-Petter, S.; Breitschopf, H.; Linington, C.; Wekerle, H.; Lassmann, H.: T-cell apoptosis in inflammatory brain lesions - Destruction of T cells does not depend on antigen recognition. American Journal of Pathology 153 (3), pp. 715 - 724 (1998)
Journal Article
Behrens, L.; Kerschensteiner, M.; Misgeld, T.; Goebels, N.; Wekerle, H.; Hohlfeld, R.: Human muscle cells express a functional costimulatory molecule distinct from B7,1 (CD80) and B7,2 (CD86) in vitro and in inflammatory lesions. The Journal of Immunology 161 (11), pp. 5943 - 5951 (1998)
Journal Article
Dang, T.; Goebels, N.; Walther, E. U.; Hohlfeld, R.: Treatment of relapsing-remitting multiple sclerosis with copolymer-1 (Glatirameracetate). Aktuelle Neurologie 25 (4), pp. 159 - 164 (1998)
Journal Article
Litzenburger, T.; Fässler, R.; Bauer, J.; Lassmann, H.; Linington, C.; Wekerle, H.; Iglesias, A.: B lymphocytes producing demyelinating autoantibodies: Development and function in gene-targeted transgenic mice. Journal of Experimental Medicine 188 (1), pp. 169 - 180 (1998)
Journal Article
Storch, M. K.; Stefferl, A.; Brehm, U.; Weissert, R.; Wallstrom, E.; Kerschensteiner, M.; Olsson, T.; Linington, C.; Lassmann, H.: Autoimmunity to myelin oligodendrocyte glycoprotein in rats mimics the spectrum of multiple sclerosis pathology. Brain Pathology 8 (4), pp. 681 - 694 (1998)
Journal Article
Utans-Schneitz, U.; Lorez, H.; Klinkert, W. E. F.; da Silva, J.; Lesslauer, W.: A novel rat CC chemokine, identified by targeted differential display, is upregulated in brain inflammation. Journal of Neuroimmunology 92 (1-2), pp. 179 - 190 (1998)
Journal Article
Wekerle, H.: The viral triggering of autoimmune disease. Nature Medicine 4 (7), pp. 770 - 771 (1998)

Book Chapter (15)

2020
Book Chapter
Burkett, P. R.; Pawlak, M.; Peters, A.; Kuchroo, V. K.: T cells and their subsets in autoimmunity. In: The autoimmune diseases, 6 Ed., pp. 91 - 116 (Eds. Rose, N. R.; Mackay, I. R.). Academic Press, London (2020)
2018
Book Chapter
Kawakami, N.: Intravital imaging of T cells within the spinal cord. In: Intravital Imaging of Dynamic Bone and Immune Systems. Methods in Molecular Biology, vol 1763, pp. 119 - 127 (Ed. Ishii, M.). Humana Press, New York (2018)
2016
Book Chapter
Burkett, P. R.; Lee, Y.; Peters, A.; Kuchroo, V. K.: Th17 and Th22 cells. In: Activation of the Immune System, Vol. 3, pp. 307 - 318 (Eds. Ratcliffe, M. J. H.; DeFranco, A.; Miyasaka, M.; Mosmann, T.) (2016)
2012
Book Chapter
Kawakami, N.; Bartholomäus, I.; Pesic, M.; Kyratsous, N. I.: Intravital Imaging of Autoreactive T Cells in Living Animals. In: LABORATORY METHODS IN CELL BIOLOGY: IMAGING, pp. 149 - 168. ELSEVIER ACADEMIC PRESS INC, 525 B STREET, SUITE 1900, SAN DIEGO, CA 92101-4495 USA (2012)
2009
Book Chapter
Derfuss, T.; Arbusow, V.; Strupp, M.; Brandt, T.; Theil, D.: The presence of lytic HSV-1 transcripts and clonally expanded T cells with a memory effector phenotype in human sensory ganglia. In: BASIC AND CLINICAL ASPECTS OF VERTIGO AND DIZZINESS, Vol. 1164, pp. 300 - 304 (Eds. Strupp, M.; Büttner, U.; Cohen, B.). BLACKWELL PUBLISHING, OXFORD (2009)
2008
Book Chapter
Bradl, M.; Dornmair, K.; Hohlfeld, R.: New tools for investigating the immunopathogenesis of MS: Principles and applications. In: Multiple Sclerosis: A Comprehensive Text, pp. 284 - 299 (Eds. Raine, C. S.; McFarland, H. F.; Hohlfeld, R.). Saunders, Elsevier, Edinburgh (2008)
2007
Book Chapter
Wekerle, H.; Flügel, A.: Demyelinating Diseases: Immunological Mechanisms in the Pathogenesis of Multiple Sclerosis. In: Molecular Neurology, pp. 475 - 497 (Ed. Waxman, S. G.). Elsevier (2007)
2006
Book Chapter
Wekerle, H.: Breaking Ignorance: The Case of the Brain. In: Current Concepts in Autoimmunity, pp. 25 - 50 (Eds. Radbruch, A.; Lipsky, P.). Springer-Verlag, Berlin-Heidelberg (2006)
2004
Book Chapter
Jenne, D. E.: Peutz-Jeghers Syndrome. In: Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine (Eds. Ganten, D.; Ruckpaul, K.; Birchmeier, W.; Epplen, J. T.; Genser, K. et al.). Springer, Berlin, Heidelberg (2004)
Book Chapter
Meinl, E.; Voltz, R.: Immunpathogenese der Multiplen Sklerose. In: Multiple Sklerose (Ed. Schmidt Hoffmann F., R.M.). Urban & Fischer (accepted)
Book Chapter
Ziemssen, T.: Neuroprotection and glatiramer acetate: The possible role in the treatment of Multiple Sclerosis. In: FRONTIERS IN CLINICAL NEUROSCIENCE: NEURODEGENERATION AND NEUROPROTECTION, pp. 111 - 134 (Ed. Vecsei, L.). KLUWER ACADEMIC/PLENUM PUBL, NEW YORK (2004)
2002
Book Chapter
Dechant, G.; Neumann, H.: Neurotrophins. In: Molecular and Cellular Biology of Neuroprotection in the CNS, Vol. 513, pp. 303 - 334 (Ed. Alzheimer, C.) (2002)
Book Chapter
Derfuss, T.; Meinl, E.: Herpesviral proteins regulating apoptosis. In: VIRAL PROTEINS COUNTERACTING HOST DEFENSES, pp. 257 - 272. SPRINGER-VERLAG BERLIN, BERLIN (2002)
2000
Book Chapter
Meinl, E.; Fleckenstein, B.: T-cell transformation by Herpesvirus saimiri. In: Effects of microbes on the immune system, pp. 439 - 451 (Eds. Cunningham, M. W.; Fujinami, R. J.). Lippincott Williams & Wilkins, Philadelphia (2000)
1998
Book Chapter
Hohlfeld, R.; Wekerle, H.: Novel therapeutic approaches to autoimmunity. In: Autoimmune Diseases, 3 Ed., pp. 833 - 847 (Eds. Rose, N. R.; Mackay, I. R.). Academic Press, San Diego, Calif. (1998)

Conference Paper (1)

2006
Conference Paper
Burrer, R.; von Herrath, M. G.; Wolfe, T.; Rempel, J. D.; Iglesias, A.; Buchmeier, M. J.: Autoantibodies exacerbate the severity of MHV-induced encephalitis. In: Nidoviruses: Toward control of SARS and other nidovirus diseases, pp. 399 - 402 (Eds. Perlamn, S.; Holmes, K. V.). 10th International Nidovirus Symposium, Colorado Springs, CO, June 25, 2005 - June 30, 2005. Springer, New York (2006)

Thesis - PhD (25)

2014
Thesis - PhD
Al Rasbi, Z.: B cell recruitment in spontaneous relapsing remitting (RR) experimental autoimmune encephalomyelitis (EAE). Dissertation, Ludwig-Maximilians-Universität, München (2014)
2013
Thesis - PhD
Koutrolos, M.: Role of Regulatory T cells in Experimental Autoimmune Encephalomyelitis - A Functional and Imaging Study. Dissertation, Ludwig-Maximilians-Universität, München (2013)
Thesis - PhD
Pesic, M.: Visualizing T cell activation around the blood-brain barrier. Dissertation, Ludwig-Maximilians-Universität, München (2013)
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