Publications of Irina Dudanova

Blumenstock, S.; Arakelyan, D.; del Grosso, N.; Schneider, S.; Shao, Y.; Gjoni, E.; Klein, R.; Dudanova, I.; Komiyama, T.: Optogenetic restoration of neuron subtype-specific cortical activity ameliorates motor deficits in Huntington’s Disease mice. bioRxiv: the preprint server for biology (2025)

Sitron, C. S.; Trinkaus, V. A.; Galesic, A.; Garhammer, M.; Checa, P. Y.; Dransfeld, U.; Feigenbutz, D.; Zhang, J.; Dudanova, I.; Harper, J. W. et al.; Hartl, F. U.: α-Synuclein aggregates inhibit ESCRT-III through sequestration and collateral degradation. bioRxiv: the preprint server for biology (2025)

Saha, I.; Yuste-Checa, P.; da Silva Padilha, M.; Guo, Q.; Korner, R.; Holthusen, H.; Trinkaus, V. A.; Dudanova, I.; Fernandez-Busnadiego, R.; Baumeister, W. et al.; Sanders, D. W.; Gautam, S.; Diamond, M. I.; Hartl, F. U.; Hipp, M. S.: The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system. Nature Communications 14, 560 (2023)

Voelkl, K.; Gutiérrez-Ángel, S.; Keeling, S.; Koyuncu, S.; da Silva Padilha, M.; Feigenbutz, D.; Arzberger, T.; Vilchez, D.; Klein, R.; Dudanova, I.: Neuroprotective effects of hepatoma-derived growth factor in models of Huntington's disease. Life science alliance 6 (11), e202302018 (2023)

Riera Tur, I.; Schäfer, T.; Hornburg, D.; Mishra, A.; da Silva Padilha, M.; Fernández-Mosquera, L.; Feigenbutz, D.; Auer, P.; Mann, M.; Baumeister, W. et al.; Klein, R.; Meissner, F.; Raimundo, N.; Fernandez-Busnadiego, R.; Dudanova, I.: Amyloid-like aggregating proteins cause lysosomal defects in neurons via gain-of-function toxicity. Life science alliance 5 (3), e202101185 (2022)

Voelkl, K.; Schulz-Trieglaff, K.; Klein, R.; Dudanova, I.: Distinct histological alterations of cortical interneuron types in mouse models of Huntington’s disease. Frontiers in Neuroscience 16, 1022251 (2022)

Blumenstock, S.; Schulz-Trieglaff, E. K.; Voelkl, K.; Bolender, A.-L.; Lapios, P.; Lindner, J.; Hipp, M. S.; Hartl, F. U.; Klein, R.; Dudanova, I.: Fluc-EGFP reporter mice reveal differential alterations of neuronal proteostasis in aging and disease. The EMBO Journal 40 (19), e107260 (2021)

Trinkaus, V. A.; Riera Tur, I.; Martinez-Sanchez, A.; Bauerlein, F. J. B.; Guo, Q.; Arzberger, T.; Baumeister, W.; Dudanova, I.; Hipp, M. S.; Hartl, F. U. et al.; Fernandez-Busnadiego, R.: In situ architecture of neuronal α-Synuclein inclusions. Nature Communications 12, 2110 (2021)

Yuste-Checa, P.; Trinkaus, V. A.; Riera Tur, I.; Imamoglu, R.; Schaller, T. F.; Wang, H.; Dudanova, I.; Hipp, M. S.; Bracher, A.; Hartl, F. U.: The extracellular chaperone Clusterin enhances Tau aggregate seeding in a cellular model. Nature Communications 12, 4863 (2021)

Blumenstock, S.; Dudanova, I.: Cortical and striatal circuits in Huntington's disease. Frontiers in Neuroscience 14, 82 (2020)

Burgold, J.; Schulz-Trieglaff, E. K.; Voelkl, K.; Gutierrez-Angel, S.; Bader, J. M.; Hosp, F.; Mann, M.; Arzberger, T.; Klein, R.; Liebscher, S. et al.; Dudanova, I.: Cortical circuit alterations precede motor impairments in Huntington's disease mice. Scientific Reports 9, 6634 (2019)

Bäuerlein, F. J. B.; Saha, I.; Mishra, A.; Kalemanov, M.; Martinez-Sanchez, A.; Klein, R.; Dudanova, I.; Hipp, M. S.; Hartl, F. U.; Baumeister, W. et al.; Fernandez-Busnadiego, R.: In situ architecture and cellular interactions of PolyQ inclusions. Cell 171 (1), pp. 179 - 187 (2017)

Hosp, F.; Gutiérrez-Ángel, S.; Schaefer, M. H.; Cox, J.; Meissner, F.; Hipp, M. S.; Hartl, F. U.; Klein, R.; Dudanova, I.; Mann, M.: Spatiotemporal proteomic profiling of Huntington’s disease inclusions reveals widespread loss of protein function. Cell Reports 21 (8), pp. 2291 - 2303 (2017)

Born, G.; Grayton, H. M.; Langhorst, H.; Dudanova, I.; Rohlmann, A.; Woodward, B. W.; Collier, D. A.; Fernandes, C.; Missler, M.: Genetic targeting of NRXN2 in mice unveils role in excitatory cortical synapse function and social behaviors. Frontiers in synaptic neuroscience 7, 3 (2015)

Schaupp, A.; Sabet, O.; Dudanova, I.; Ponserre, M.; Bastiaens, P.; Klein, R.: The composition of EphB2 clusters determines the strength in the cellular repulsion response. The Journal of Cell Biology 204 (3), pp. 409 - 422 (2014)

Dudanova, I.; Klein, R.: Integration of guidance cues: Parallel signaling and crosstalk. Trends in Neurosciences 36 (5), pp. 295 - 304 (2013)

Gatto, G.; Dudanova, I.; Suetterlin, P.; Davies, A. M.; Drescher, U.; Bixby, J. L.; Klein, R.: Protein tyrosine phosphatase receptor type O inhibits trigeminal axon growth and rranching by repressing TrkB and ret signaling. The Journal of Neuroscience 33 (12), pp. 5399 - 5410 (2013)

Dudanova, I.; Kao, T.-J.; Herrmann, J. E.; Zheng, B.; Kania, A.; Klein, R.: Genetic evidence for a contribution of EphA: EphrinA reverse signaling to motor axon guidance. The Journal of Neuroscience 32 (15), pp. 5209 - 5215 (2012)

Dudanova, I.; Klein, R.: The axon's balancing act: Cis- and trans-interactions between Ephs and Ephrins. Neuron 71 (1), pp. 1 - 3 (2011)

Dudanova, I.; Gatto, G.; Klein, R.: GDNF acts as a chemoattractant to support ephrinA-induced repulsion of limb motor axons. Current Biology 20 (23), pp. 2150 - 2156 (2010)

Medrihan, L.; Tantalaki, E.; Aramuni, G.; Sargsyan, V.; Dudanova, I.; Missler, M.; Zhang, W.: Early defects of GABAergic synapses in the brain stem of a MeCP2 mouse model of Rett syndrome. Journal of Neurophysiology 99 (1), pp. 112 - 121 (2008)

Dudanova, I.; Tabuchi, K.; Rohlmann, A.; Südhof, T. C.; Missler, M.: Deletion of α-neurexins does not cause a major impairment of axonal pathfinding or synapse formation. The Journal of Comparative Neurology 502 (2), pp. 261 - 274 (2007)

Dudanova, I.; Sedej, S.; Ahmad, M.; Masius, H.; Sargsyan, V.; Zhang, W. Q.; Riedel, D.; Angenstein, F.; Schild, D.; Rupnik, M. et al.; Missler, M.: Important contribution of α-neurexins to Ca2+-triggered exocytosis of secretory granules. The Journal of Neuroscience 26 (41), pp. 10599 - 10613 (2006)

Piechotta, K.; Dudanova, I.; Missler, M.: The resilient synapse: Insights from genetic interference of synaptic cell adhesion molecules. Cell and Tissue Research 326, pp. 617 - 642 (2006)

Gaitanos, T.; Dudanova, I.; Sakkou, M.; Klein, R.; Paixao, S.: The Eph receptor family. In: Receptor tyrosine kinases: Family and subfamilies, pp. 165 - 264 (Eds. Wheeler, D. L.; Yarden, Y.). Springer International Publishing, Cham (2015)

Blumenstock, S.; Dudanova, I.: Balancing neuronal circuits. Science 377 (6613), pp. 1383 - 1384 (2022)

Dudanova, I.: Biosensors for studying neuronal proteostasis. Frontiers in Molecular Neuroscience 15, 829365 (2022)