Max Planck Institute for Biological Intelligence

Publications of Rüdiger Klein

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Journal Article (190)

51.

Journal Article

Seiradake, E.; Schaupp, A.; del Toro Ruiz, D.; Kaufmann, R.; Mitakidis, N.; Harlos, K.; Aricescu, A. R.; Klein, R.; Jones, E. Y.: Structurally encoded intraclass differences in EphA clusters drive distinct cell responses. Nature Structural and Molecular Biology 20 (8), pp. 958 - 964 (2013)

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52.

Journal Article

Dudanova, I.; Kao, T.-J.; Herrmann, J. E.; Zheng, B.; Kania, A.; Klein, R.: Genetic evidence for a contribution of EphA: EphrinA reverse signaling to motor axon guidance. The Journal of Neuroscience 32 (15), pp. 5209 - 5215 (2012)

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53.

Journal Article

Fontana, X.; Hristova, M.; Da Costa, C.; Patodia, S.; Thei, L.; Makwana, M.; Spencer-Dene, B.; Latouche, M.; Mirsky, R.; Jessen, K. R. et al.; Klein, R.; Raivich, G.; Behrens, A.: C-Jun in Schwann cells promotes axonal regeneration and motoneuron survival via paracrine signaling. The Journal of Cell Biology 198 (1), pp. 127 - 141 (2012)

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54.

Journal Article

Klein, R.: Eph/ephrin signalling during development. Development 139 (22), pp. 4105 - 4109 (2012)

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55.

Journal Article

Aron, L.; Klein, R.: Repairing the parkinsonian brain with neurotrophic factors. Trends in Neurosciences 34 (2), pp. 88 - 100 (2011)

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56.

Journal Article

Dudanova, I.; Klein, R.: The axon's balancing act: Cis- and trans-interactions between Ephs and Ephrins. Neuron 71 (1), pp. 1 - 3 (2011)

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57.

Journal Article

Peng, C.; Aron, L.; Klein, R.; Li, M.; Wurst, W.; Prakash, N.; Le, W.: Pitx3 is a critical mediator of GDNF-induced BDNF expression in nigrostriatal dopaminergic neurons. The Journal of Neuroscience 31 (36), pp. 12802 - 12815 (2011)

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58.

Journal Article

Wang, L.; Klein, R.; Zheng, B. H.; Marquardt, T.: Anatomical coupling of sensory and motor nerve trajectory via axon tracking. Neuron 71 (2), pp. 263 - 277 (2011)

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59.

Journal Article

Yamagishi, S.; Hampel, F.; Hata, K.; del Toro Ruiz, D.; Schwark, M.; Kvachnina, E.; Bastmeyer, M.; Yamashita, T.; Tarabykin, V.; Klein, R. et al.; Egea, J.: FLRT2 and FLRT3 act as repulsive guidance cues for Unc5-positive neurons. The EMBO Journal 30 (14), pp. 2920 - 2933 (2011)

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60.

Journal Article

Zhai, J.; Zhou, W.; Li, J.; Hayworth, C. R.; Zhang, L.; Misawa, H.; Klein, R.; Scherer, S. S.; Balice-Gordon, R. J.; Kalb, R. G.: The in vivo contribution of motor neuron TrkB receptors to mutant SOD1 motor neuron disease. Human Molecular Genetics 20 (21), pp. 4116 - 4131 (2011)

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61.

Journal Article

Aron, L.; Klein, P.; Pham, T. T.; Kramer, E. R.; Wurst, W.; Klein, R.: Pro-survival role for Parkinson's associated gene DJ-1 revealed in trophically impaired dopaminergic neurons. PLoS Biology 8 (4), e1000349 (2010)

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62.

Journal Article

Bashaw, G. J.; Klein, R.: Signaling from axon guidance receptors. Cold Spring Harbor Perspectives in Biology 2 (5), a001941 (2010)

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63.

Journal Article

Dudanova, I.; Gatto, G.; Klein, R.: GDNF acts as a chemoattractant to support ephrinA-induced repulsion of limb motor axons. Current Biology 20 (23), pp. 2150 - 2156 (2010)

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64.

Journal Article

Griciuc, A.; Aron, L.; Roux, M. J.; Klein, R.; Giangrande, A.; Ueffing, M.: Inactivation of VCP/ter94 suppresses retinal pathology caused by misfolded Rhodopsin in Drosophila. PLoS Genetics 6 (8), e1001075 (2010)

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65.

Journal Article

Klein, R.: Cell sorting during regenerative tissue formation. Cell 143 (1), pp. 32 - 34 (2010)

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66.

Journal Article

Klein, R.: Topography in hippocampal mossy fiber plasticity. Neuron 65 (5), pp. 580 - 582 (2010)

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67.

Journal Article

Paixao, S.; Klein, R.: Neuron-astrocyte communication and synaptic plasticity. Current Opinion in Neurobiology 20 (4), pp. 466 - 473 (2010)

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68.

Journal Article

Filosa, A.; Paixao, S.; Honsek, S. D.; Carmona, M. A.; Becker, L.; Feddersen, B.; Gaitanos, L.; Rudhard, Y.; Schoepfer, R.; Klopstock, T. et al.; Kullander, K.; Rose, C. R.; Pasquale, E. B.; Klein, R.: Neuron-glia communication via EphA4/ephrin-A3 modulates LTP through glial glutamate transport. Nature Neuroscience 12 (10), pp. 1285 - 1292 (2009)

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69.

Journal Article

Klein, R.: Bidirectional modulation of synaptic functions by Eph/ephrin signaling. Nature Neuroscience 12 (1), pp. 15 - 20 (2009)

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70.

Journal Article

Strelau, J.; Strzelczyk, A.; Rusu, P.; Bendner, G.; Wiese, S.; Diella, F.; Altick, A. L.; von Bartheld, C. S.; Klein, R.; Sendtner, M. et al.; Unsicker, K.: Progressive postnatal motoneuron loss in mice lacking GDF-15. The Journal of Neuroscience 29 (43), pp. 13640 - 13648 (2009)

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71.

Journal Article

Deininger, K.; Eder, M.; Kramer, E. R.; Zieglgänsberger, W.; Dodt, H. U.; Dornmair, K.; Colicelli, J.; Klein, R.: The Rab5 guanylate exchange factor Rin1 regulates endocytosis of the EphA4 receptor in mature excitatory neurons. Proceedings of the National Academy of Sciences of the United States of America 105 (34), pp. 12539 - 12544 (2008)

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72.

Journal Article

Egea, J.; Erlacher, C.; Montanez, E.; Burtscher, I.; Yamagishi, S.; Hess, M.; Hampel, F.; Sanchez, R.; Rodriguez-Manzaneque, M. T.; Bösl, M. R. et al.; Faessler, R.; Lickert, H.; Klein, R.: Genetic ablation of FLRT3 reveals a novel morphogenetic function for the anterior visceral endoderm in suppressing mesoderm differentiation. Genes and Development 22 (23), pp. 3349 - 3362 (2008)

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73.

Journal Article

Essmann, C. L.; Martinez, E.; Geiger, J. C.; Zimmer, M.; Traut, M. H.; Stein, V.; Klein, R.; Acker-Palmer, A.: Serine phosphorylation of ephrinB2 regulates trafficking of synaptic AMPA receptors. Nature Neuroscience 11 (9), pp. 1035 - 1043 (2008)

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74.

Journal Article

Hulshagen, L.; Krysko, O.; Bottelbergs, A.; Huyghe, S.; Klein, R.; Van Veldhoven, P. P.; De Deyn, P. P.; D'Hooge, R.; Hartmann, D.; Baes, M.: Absence of functional peroxisomes from mouse CNS causes dysmyelination and axon degeneration. The Journal of Neuroscience 28 (15), pp. 4015 - 4027 (2008)

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75.

Journal Article

Kappeler, L.; Filho, C. D. M.; Dupont, J.; Leneuve, P.; Cervera, P.; Perin, L.; Loudes, C.; Blaise, A.; Klein, R.; Epelbaum, J. et al.; Le Bouc, Y.; Holzenberger, M.: Brain IGF-1 receptors control mammalian growth and lifespan through a neuroendocrine mechanism. PLoS Biology 6 (10), e254, pp. 2144 - 2153 (2008)

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76.

Journal Article

Mishra, A.; Knerr, B.; Paixao, S.; Kramer, E. R.; Klein, R.: The protein dendrite arborization and synapse maturation 1 (Dasm-1) is dispensable for dendrite arborization. Molecular and Cellular Biology (Washington, DC) 28 (8), pp. 2782 - 2791 (2008)

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77.

Journal Article

Wilkinson, G. A.; Schittny, J. C.; Reinhardt, D. P.; Klein, R.: Role for ephrinB2 in postnatal lung alveolar development and elastic matrix integrity. Developmental Dynamics 237 (8), pp. 2220 - 2234 (2008)

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78.

Journal Article

Bouzioukh, F.; Wilkinson, G. A.; Adelmann, G.; Frotscher, M.; Stein, V.; Klein, R.: Tyrosine phosphorylation sites in ephrinB2 are required for hippocampal long-term potentiation but not long-term depression. The Journal of Neuroscience 27 (42), pp. 11279 - 11288 (2007)

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79.

Journal Article

Cull-Candy, S.; Klein, R.: Signalling mechanisms. Current Opinion in Neurobiology 17 (3), pp. 277 - 280 (2007)

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80.

Journal Article

Egea, J.; Klein, R.: Bidirectional Eph-ephrin signaling during axon guidance. Trends in Cell Biology 17 (5), pp. 230 - 238 (2007)

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81.

Journal Article

Ke, Y. H.; Zhang, E. E.; Hagihara, K.; Wu, D. M.; Pang, Y. H.; Klein, R.; Curran, T.; Ranscht, B.; Feng, G. S.: Deletion of Shp2 in the brain leads to defective proliferation and differentiation in neural stem cells and early postnatal lethality. Molecular and Cellular Biology (Washington, DC) 27 (19), pp. 6706 - 6717 (2007)

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82.

Journal Article

Kowsky, S.; Poppelmeyer, C.; Kramer, E. R.; Falkenburger, B. H.; Kruse, A.; Klein, R.; Schulz, J. B.: RET signaling does not modulate MPTP toxicity but is required for regeneration of dopaminergic axon terminals. Proceedings of the National Academy of Sciences of the United States of America 104 (50), pp. 20049 - 20054 (2007)

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83.

Journal Article

Kramer, E. R.; Aron, L.; Ramakers, G. M. J.; Seitz, S.; Zhuang, X. X.; Beyer, K.; Smidt, M. P.; Klein, R.: Absence of ret signaling in mice causes progressive and late degeneration of the nigrostriatal system. PLoS Biology 5 (3), e39, pp. 616 - 628 (2007)

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84.

Journal Article

Krysko, O.; Hulshagen, L.; Janssen, A.; Schutz, G.; Klein, R.; De Bruycker, M.; Espeel, M.; Gressens, P.; Baes, M.: Neocortical and cerebellar developmental abnormalities in conditions of selective elimination of peroxisomes from brain or from liver. Journal of Neuroscience Research 85 (1), pp. 58 - 72 (2007)

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85.

Journal Article

Wegmeyer, H.; Egea, J.; Rabe, N.; Gezelius, H.; Filosa, A.; Enjin, A.; Varoqueaux, F.; Deininger, K.; Schnuetgen, F.; Brose, N. et al.; Klein, R.; Kullander, K.; Betz, A.: EphA4-dependent axon guidance is mediated by the RacGAP alpha2-chimaerin. Neuron 55 (5), pp. 756 - 767 (2007)

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86.

Journal Article

Ambrosino, C.; Iwata, T.; Scafoglio, C.; Mallardo, M.; Klein, R.; Nebreda, A. R.: TEF-1 and C/EBPβ are major p38α MAPK-regulated transcription factors in proliferating cardiomyocytes. Biochemical Journal 396 (1), pp. 163 - 172 (2006)

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87.

Journal Article

Angrand, P. O.; Segura, I.; Volkel, P.; Ghidelli, S.; Terry, R.; Brajenovic, M.; Vintersten, K.; Klein, R.; Superti-Furga, G.; Drewes, G. et al.; Kuster, B.; Bouwmeester, T.; Acker-Palmer, A.: Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling. Molecular and Cellular Proteomics 5 (12), pp. 2211 - 2227 (2006)

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88.

Journal Article

Dufour, A.; Egea, J.; Kullander, K.; Klein, R.; Vanderhaeghen, P.: Genetic analysis of EphA-dependent signaling mechanisms controlling topographic mapping in vivo. Development 133 (22), pp. 4415 - 4420 (2006)

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89.

Journal Article

Ferby, I.; Reschke, M.; Kudlacek, O.; Knyazev, P.; Pante, G.; Amann, K.; Sommergruber, W.; Kraut, N.; Ullrich, A.; Faessler, R. et al.; Klein, R.: Mig6 is a negative regulator of EGF receptor-mediated skin morphogenesis and tumor formation. Nature Medicine 12 (5), pp. 568 - 573 (2006)

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90.

Journal Article

Kadison, S. R.; Mäkinen, T.; Klein, R.; Henkemeyer, M.; Kaprielian, Z.: EphB receptors and ephrin-B3 regulate axon guidance at the ventral midline of the embryonic mouse spinal cord. The Journal of Neuroscience 26 (35), pp. 8909 - 8914 (2006)

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91.

Journal Article

Kramer, E. R.; Knott, L.; Su, F. Y.; Dessaud, E.; Krull, C. E.; Helmbacher, F.; Klein, R.: Cooperation between GDNF/Ret and ephrinA/EphA4 signals for motor-axon pathway selection in the limb. Neuron 50 (1), pp. 35 - 47 (2006)

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92.

Journal Article

Lauterbach, J.; Klein, R.: Release of full-length EphB2 receptors from hippocampal neurons to cocultured glial cells. The Journal of Neuroscience 26 (45), pp. 11575 - 11581 (2006)

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93.

Journal Article

Diehl, S.; Bruno, R.; Wilkinson, G. A.; Loose, D.; Wilting, J.; Schweigerer, L.; Klein, R.: Altered expression patterns of EphrinB2 and EphB2 in human umbilical vessels and congenital venous malformations. Pediatric Research 57 (4), pp. 537 - 544 (2005)

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94.

Journal Article

Egea, J.; Nissen, U. V.; Dufour, A.; Sahin, M.; Greer, P.; Kullander, K.; Mrsic-Flogel, T. D.; Greenberg, M. E.; Kiehn, O.; Vanderhaeghen, P. et al.; Klein, R.: Regulation of EphA4 kinase activity is required for a subset of axon guidance decisions suggesting a key role for receptor clustering in Eph function. Neuron 47 (4), pp. 515 - 528 (2005)

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95.

Journal Article

Klein, R.: Axon guidance: Opposing EPHects in the growth cone. Cell 121 (1), pp. 4 - 6 (2005)

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96.

Journal Article

Mäkinen, T.; Adams, R. H.; Bailey, J.; Lu, Q.; Ziemiecki, A.; Alitalo, K.; Klein, R.; Wilkinson, G. A.: PDZ interaction site in ephrinB2 is required for the remodeling of lymphatic vasculature. Genes and Development 19 (3), pp. 397 - 410 (2005)

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97.

Journal Article

Pante, G.; Thompson, J.; Lamballe, F.; Iwata, T.; Ferby, I.; Barr, F. A.; Davies, A. M.; Maina, F.; Klein, R.: Mitogen-inducible gene 6 is an endogenous inhibitor of HGF/Met-induced cell migration and neurite growth. The Journal of Cell Biology 171 (2), pp. 337 - 348 (2005)

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98.

Journal Article

Anton, E. S.; Ghashghaei, H. T.; Weber, J. L.; McCann, C.; Fischer, T. M.; Cheung, I. D.; Gassmann, M.; Messing, A.; Klein, R.; Schwab, M. H. et al.; Lloyd, K. C. K.; Lai, C.: Receptor tyrosine kinase ErbB4 modulates neuroblast migration and placement in the adult forebrain. Nature Neuroscience 7 (12), pp. 1319 - 1328 (2004)

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99.

Journal Article

Grunwald, I. C.; Korte, M.; Adelmann, G.; Plueck, A.; Kullander, K.; Adams, R. H.; Frotscher, M.; Bonhoeffer, T.; Klein, R.: Hippocampal plasticity requires postsynaptic ephrinBs. Nature Neuroscience 7 (1), pp. 33 - 40 (2004)

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100.

Journal Article

Klein, R.: Eph/ephrin signaling in morphogenesis, neural development and plasticity. Current Opinion in Cell Biology 16 (5), pp. 580 - 589 (2004)

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