Publications of D. E. Jenne

Romero, V.; Fellows, E.; Jenne, D. E.; Andrade, F.: Cleavage of La protein by granzyme H induces cytoplasmic translocation and interferes with La-mediated HCV-IRES translational activity. Cell Death and Differentiation 16 (2), pp. 340 - 348 (2009)

Kessenbrock, K.; Fröhlich, L.; Sixt, M.; Lämmermann, T.; Pfister, H.; Bateman, A.; Belaaouaj, A.; Ring, J.; Ollert, M.; Fässler, R. et al.; Jenne, D. E.: Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin. Journal of Clinical Investigation 118 (7), pp. 2438 - 2447 (2008)

Korkmaz, B.; Kuhl, A.; Bayat, B.; Santoso, S.; Jenne, D. E.: A Hydrophobic Patch on Proteinase 3, the Target of Autoantibodies in Wegener Granulomatosis, Mediates Membrane Binding via NB1 Receptors. Journal of Biological Chemistry 283 (51), pp. 35976 - 35982 (2008)

Kuhl, A.; Melberg, A.; Meinl, E.; Nürnberg, G.; Nürnberg, P.; Kehrer-Sawatzki, H.; Jenne, D. E.: Myofibrillar myopathy with arrhythmogenic right ventricular cardiomyopathy 7: Corroboration and narrowing of the critical region on 10q22.3. European Journal of Human Genetics 16, pp. 367 - 373 (2008)

Kurschus, F. C.; Fellows, E.; Stegmann, E.; Jenne, D. E.: Granzyme B delivery via perforin is restricted by size, but not by heparan sullfate-dependent endocytosis. Proceedings of the National Academy of Sciences of the United States of America 105 (37), pp. 13799 - 13804 (2008)

Riedl, J.; Crevenna, A. H.; Kessenbrock, K.; Yu, J. H.; Neukirchen, D.; Bista, M.; Bradke, F.; Jenne, D. E.; Holak, T. A.; Werb, Z. et al.; Sixt, M.; Wedlich-Söldner, R.: Lifeact: A versatile marker to visualize F-actin. Nature Methods 5 (7), pp. 605 - 607 (2008)

Andrade, F.; Fellows, E.; Jenne, D. E.; Rosen, A.; Young, C. S.: Granzyme H destroys the function of critical adenoviral proteins required for viral DNA replication and granzyme B inhibition. The EMBO Journal 26 (8), pp. 2148 - 2157 (2007)

Fellows, E.; Gil-Parrado, S.; Jenne, D. E.; Kurschus, F. C.: Natural killer cell-derived human granzyme H induces an alternative, caspase-independent cell-death program. Blood 110 (2), pp. 544 - 552 (2007)

Jarius, S.; Eichhorn, P.; Albert, M. H.; Wagenpfeil, S.; Wick, M.; Belohradsky, B. H.; Hohlfeld, R.; Jenne, D. E.; Voltz, R.: Intravenous immunoglobulins contain naturally occurring antibodies that mimic antineutrophil cytoplasmic antibodies and activate neutrophils in a TNFα-dependent and Fc-receptor-independent way. Blood 109 (10), pp. 4376 - 4382 (2007)

Jenne, D. E.; Aries, P. M.; Einwächter, S.; Akkad, A. D.; Wieczorek, S.; Lamprecht, P.; Gross, W. L.: The low-penetrance R92Q mutation of the tumour necrosis factor superfamily 1A gene is neither a major risk factor for Wegener's granulomatosis nor multiple sclerosis. Annals of the Rheumatic Diseases 66 (9), pp. 1266 - 1267 (2007)

Jenne, D. E.; Kuhl, A.: Production and applications of recombinant proteinase 3, Wegener's autoantigen: Problems and perspectives. Clinical Nephrology 66 (3), pp. 153 - 159 (2006)

Bade, B.; Boettcher, H. E.; Lohrmann, J.; Hink-Schauer, C.; Bratke, K.; Jenne, D. E.; Virchow, J. C.; Luttmann, W.: Differential expression of the granzymes A, K and M and perforin in human peripheral blood lymphocytes. International Immunology 17 (11), pp. 1419 - 1428 (2005)

Jenne, D. E.; Kley, R. A.; Vorgerd, M.; Schroder, J. M.; Weis, J.; Reimann, H.; Albrecht, B.; Nurnberg, P.; Thiele, H.; Muller, C. R. et al.; Meng, G.; Witt, C. C.; Labeit, S.: Limb girdle muscular dystrophy in a sibling pair with a homozygous Ser606Leu mutation in the alternatively spliced IS2 region of calpain 3. Biological Chemistry 386 (1), pp. 61 - 67 (2005)

Krumbholz, M.; Specks, U.; Wick, M.; Kalled, S. L.; Jenne, D. E.; Meinl, E.: BAFF is elevated in serum of patients with Wegener's granulomatosis. Journal of Autoimmunity 25 (4), pp. 298 - 302 (2005)

Kurschus, F. C.; Bruno, R.; Fellows, E.; Falk, C. S.; Jenne, D. E.: Membrane receptors are not required to deliver granzyme B during killer cell attack. Blood 105 (5), pp. 2049 - 2058 (2005)

Schuller, M.; Jenne, D. E.; Voltz, R.: The human PNMA family: Novel neuronal proteins implicated in paraneoplastic neurological disease. Journal of Neuroimmunology 169 (1-2), pp. 172 - 176 (2005)

Spiegel, M.; Oexle, K.; Horn, D.; Windt, E.; Buske, A.; Albrecht, B.; Prott, E. C.; Seemanova, E.; Seidel, J.; Rosenbaum, T. et al.; Jenne, D. E.; Kehrer-Sawatzki, H. K.; Tinschert, S.: Childhood overgrowth in patients with common NF1 microdeletions. European Journal of Human Genetics 13 (7), pp. 883 - 888 (2005)

Wiesner, O.; Litwiller, R. D.; Hummel, A. M.; Viss, M. A.; McDonald, C. J.; Jenne, D. E.; Fass, D. N.; Specks, U.: Differences between human proteinase 3 and neutrophil elastase and their murine homologues are relevant for murine model experiments. FEBS Letters 579 (24), pp. 5305 - 5312 (2005)

Kehrer-Sawatzki, H.; Kluwe, L.; Sandig, C.; Kohn, M.; Wimmer, K.; Krammer, U.; Peyrl, A.; Jenne, D. E.; Hansmann, I.; Mautner, V. F.: High frequency of mosaicism among patients with neurofibromatosis type 1 (NF1) with microdeletions caused by somatic recombination of the JJAZ1 gene. American Journal of Human Genetics 75 (3), pp. 410 - 423 (2004)

Kurschus, F. C.; Kleinschmidt, M.; Fellows, E.; Dornmair, K.; Rudolph, R.; Lilie, H.; Jenne, D. E.: Killing of target cells by redirected granzyme B in the absence of perforin. FEBS Letters 562 (1-3), pp. 87 - 92 (2004)

Pfister, H.; Ollert, M.; Fröhlich, L. O.; Quintanilla-Fend, L.; Colby, T. V.; Specks, U.; Jenne, D. E.: Autoantibodies against the murine homolog of Wegener’s autoantigen (proteinase 3) are pathogenic in vivo. Blood 104, pp. 1411 - 1418 (2004)

Pfister, H.; Ollert, M.; Fröhlich, L. F.; Quintanilla-Martinez, L.; Colby, T. V.; Specks, U.; Jenne, D. E.: Antineutrophil cytoplasmic autoantibodies against the murine homolog of proteinase 3 (Wegener autoantigen) are pathogenic in vivo. Blood 104 (5), pp. 1411 - 1418 (2004)

Wiesner, O.; Russell, K. A.; Lee, A. S.; Jenne, D. E.; Trimarchi, M.; Gregorini, G.; Specks, U.: Antineutrophil cytoplasmic antibodies reacting with human neutrophil elastase as a diagnostic marker for cocaine-induced midline destructive lesions but not autoimmune vasculitis. Arthritis and Rheumatism 50 (9), pp. 2954 - 2965 (2004)

Hink-Schauer, C.; Estebanez-Perpina, E.; Kurschus, F. C.; Bode, W.; Jenne, D. E.: Crystal structure of the apoptosis-inducing human granzyme A dimer. Nature Structural Biology 10 (7), pp. 535 - 540 (2003)

Jenne, D. E.; Tinschert, S.; Dorschner, M. O.; Hameister, H.; Stephens, K.; Kehrer-Sawatzki, H.: Complete physical map and gene content of the human NFI tumor suppressor region in human and mouse. Genes Chromosomes & Cancer 37 (2), pp. 111 - 120 (2003)

Kehrer-Sawatzki, H.; Tinschert, S.; Jenne, D. E.: Heterogeneity of breakpoints in non-LCR-mediated large constitutional deletions of the 17q11.2 NF1 tumour suppressor region. Journal of Medical Genetics 40 (10), e116 (2003)

Petek, E.; Jenne, D. E.; Smolle, J.; Binder, B.; Lasinger, W.; Windpassinger, C.; Wagner, K.; Kroisel, P. M.; Kehrer-Sawatzki, H.: Mitotic recombination mediated by the JJAZF1 (KIAA0160) gene causing somatic mosaicism and a new type of constitutional NF1 microdeletion in two children of a mosaic female with only few manifestations. Journal of Medical Genetics 40 (7), pp. 520 - 525 (2003)

Burger, B.; Uhlhaas, S.; Mangold, E.; Propping, P.; Friedl, W.; Jenne, D. E.; Dockter, G.; Back, W.: Novel de novo mutation of MADH4/SMAD4 in a patient with juvenile polyposis. American Journal of Medical Genetics 110 (3), pp. 289 - 291 (2002)

Campbell, P. K.; Waymire, K. G.; Heier, R. L.; Sharer, C.; Day, D. E.; Reimann, H.; Jaje, J. M.; Friedrich, G. A.; Burmeister, M.; Bartness, T. J. et al.; Russell, L. D.; Young, L. J.; Zimmer, M.; Jenne, D. E.; MacGregor, G. R.: Mutation of a novel gene results in abnormal development of spermatid flagella, loss of intermale aggression and reduced body fat in mice. Genetics 162 (1), pp. 307 - 320 (2002)

Hink-Schauer, C.; Estebanez-Perpina, E.; Wilharm, E.; Fuentes-Prior, P.; Klinkert, W. E. F.; Bode, W.; Jenne, D. E.: The 2.2-angstrom crystal structure of human pro-granzyme K reveals a rigid zymogen with unusual features. Journal of Biological Chemistry 277 (52), pp. 50923 - 50933 (2002)

Jishage, K.; Nezu, J.; Kawase, Y.; Iwata, T.; Watanabe, M.; Miyoshi, A.; Ose, A.; Habu, K.; Kake, T.; Kamada, N. et al.; Ueda, O.; Kinoshita, M.; Jenne, D. E.; Shimane, M.; Suzuki, H.: Role of Lkb1, the causative gene of Peutz-Jegher's syndrome, in embryogenesis and polyposis. Proceedings of the National Academy of Sciences of the United States of America 99 (13), pp. 8903 - 8908 (2002)

Wilharm, E.; Tschopp, J.; Jenne, D. E.: Biological activities of granzyme K are conserved in the mouse and account for residual Z-Lys-SBzl activity in granzyme A-deficient mice. FEBS Letters 459 (1), pp. 139 - 142 (1999)

Jenne, D. E.: Peutz-Jeghers Syndrome. In: Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine (Eds. Ganten, D.; Ruckpaul, K.; Birchmeier, W.; Epplen, J. T.; Genser, K. et al.). Springer, Berlin, Heidelberg (2004)

Granel, J.; Korkmaz, B.; Nouar, D.; Weiss, S. A. I.; Jenne, D. E.; Lemoine, R.; Hoarau, C.: Pathogenicity of proteinase 3-anti-neutrophil cytoplasmic antibody in granulomatosis with polyangiitis: Implications as biomarker and future therapies. Frontiers in immunology 12, 571933 (2021)

Korkmaz, B.; Lamort, A.-S.; Domain, R.; Beauvillain, C.; Gieldon, A.; Yildirim, A. O.; Stathopoulos, G. T.; Rhimi, M.; Jenne, D. E.; Kettritz, R.: Cathepsin C inhibition as a potential treatment strategy in cancer. Biochemical Pharmacology 194, p. 114803 - 114803 (2021)

Weiss, S. A. I.; Rehm, S. R. T.; Perera, N. C.; Biniossek, M. L.; Schilling, O.; Jenne, D. E.: Origin and expansion of the serine protease repertoire in the myelomonocyte lineage. International Journal of Molecular Sciences 22 (4), 1658 (2021)