Publications of Winfried Denk
All genres
Journal Article (109)
2024
Journal Article
An anatomical substrate of credit assignment in reinforcement learning. bioRxiv: the preprint server for biology (2024)
2022
Journal Article
19 (11), pp. 1357 - 1366 (2022)
Automated synapse-level reconstruction of neural circuits in the larval zebrafish brain. Nature Methods 2020
Journal Article
182 (6), pp. 1372 - 1376 (2020)
The mind of a mouse. Cell 2018
Journal Article
13 (11), e0207828 (2018)
Full reconstruction of large lobula plate tangential cells in Drosophila from a 3D EM dataset. PLoS One
Journal Article
15 (8), pp. 605 - 610 (2018)
High-precision automated reconstruction of neurons with flood-filling networks. Nature Methods
Journal Article
50, pp. 261 - 267 (2018)
Progress and remaining challenges in high-throughput volume electron microscopy. Current Opinion in Neurobiology
Journal Article
23 (10), pp. 2942 - 2954 (2018)
Volume EM reconstruction of spinal cord reveals wiring specificity in speed-related motor circuits. Cell Reports 2017
Journal Article
6, e24364 (2017)
EM connectomics reveals axonal target variation in a sequence-generating network. eLife
Journal Article
6, e25648 (2017)
Single-protein detection in crowded molecular environments in cryo-EM images. eLife 2015
Journal Article
12 (6), pp. 541 - 546 (2015)
High-resolution whole-brain staining for electron microscopic circuit reconstruction. Nature Methods 2014
Journal Article
509 (7500), pp. 331 - 336 (2014)
Space-time wiring specificity supports direction selectivity in the retina. Nature 2013
Journal Article
19 (1), pp. 38 - 55 (2013)
Low-dosage maximum-a-posteriori focusing and stigmation. Microscopy and Microanalysis
Journal Article
2013 (10), pp. 904 - 913 (2013)
Miniaturization of two-photon microscopy for imaging in freely moving animals. Cold Spring Harbor Protocols
Journal Article
500 (7461), pp. 168 - 174 (2013)
Connectomic reconstruction of the inner plexiform layer in the mouse retina. Nature
Journal Article
250 (2), pp. 101 - 110 (2013)
Automated in-chamber specimen coating for serial block-face electron microscopy. Journal of Microscopy 2012
Journal Article
16 (4), pp. 796 - 805 (2012)
3D segmentation of SBFSEM images of neuropil by a graphical model over supervoxel boundaries. Medical Image Analysis
Journal Article
13 (10), pp. 669 - 673 (2012)
An interview with...: The Kavli prize winners. Nature Reviews Neuroscience
Journal Article
13 (5), pp. 351 - 358 (2012)
Structural neurobiology: Missing link to a mechanistic understanding of neural computation. Nature Reviews Neuroscience
Journal Article
22 (1), pp. 1 - 2 (2012)
Neurotechnology: Summa technologiae. Current Opinion in Neurobiology
Journal Article
9 (12), pp. 1198 - 1201 (2012)
Staining and embedding the whole mouse brain for electron microscopy. Nature Methods 2011
Journal Article
471 (7337), pp. 183 - 188 (2011)
Wiring specificity in the direction-selectivity circuit of the retina. Nature
Journal Article
14 (8), pp. 1081 - 1088 (2011)
High-accuracy neurite reconstruction for high-throughput neuroanatomy. Nature Neuroscience
Journal Article
31 (45), pp. 16125 - 16138 (2011)
Large-scale automated histology in the pursuit of connectomes. The Journal of Neuroscience
Journal Article
334 (6056), pp. 618 - 623 (2011)
The big and the small: Challenges of imaging the brain's circuits. Science
Journal Article
14 (8), pp. 1089 - 1093 (2011)
Two-photon calcium imaging of evoked activity from L5 somatosensory neurons in vivo. Nature Neuroscience
Journal Article
100 (1), pp. 232 - 242 (2011)
Second-harmonic generation imaging of membrane potential with retinal analogues. Biophysical Journal 2010
Journal Article
18 (5), pp. 4222 - 4239 (2010)
High speed optical coherence microscopy with autofocus adjustment and a miniaturized endoscopic imaging probe. Optics Express
Journal Article
22 (2), pp. 511 - 538 (2010)
Convolutional networks can learn to generate affinity graphs for image segmentation. Neural computation 2009
Journal Article
457 (6), pp. 1393 - 1414 (2009)
Eyecup Scope - Optical recordings of light stimulus-evoked fluorescence signals in the retina. Pflügers Archiv: European Journal of Physiology
Journal Article
13 (1), pp. 180 - 188 (2009)
Axon tracking in serial block-face scanning electron microscopy. Medical Image Analysis
Journal Article
106 (46), pp. 19557 - 19562 (2009)
Visually evoked activity in cortical cells imaged in freely moving animals. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
64 (5), pp. 719 - 729 (2009)
Rapid axonal sprouting and pruning accompany functional reorganization in primary visual cortex. Neuron 2008
Journal Article
18 (6), pp. 633 - 641 (2008)
3D structural imaging of the brain with photons and electrons. Current Opinion in Neurobiology
Journal Article
9 (3), pp. 195 - 205 (2008)
Imaging in vivo: Watching the brain in action. Nature Reviews Neuroscience
Journal Article
5 (1), pp. 61 - 67 (2008)
Targeted patch−clamp recordings and single−cell electroporation of unlabeled neurons in vivo. Nature Methods
Journal Article
105 (21), pp. 7588 - 7593 (2008)
In vivo two−photon voltage−sensitive dye imaging reveals top−down control of cortical layers 1 and 2 during wakefulness. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
167 (2), pp. 349 - 357 (2008)
Contour-propagation algorithms for semi-automated reconstruction of neural processes. Journal of Neuroscience Methods
Journal Article
99 (5), pp. 2584 - 2601 (2008)
Spatiotemporally graded NMDA spike/plateau potentials in basal dendrites of neocortical pyramidal neurons. Journal of Neurophysiology
Journal Article
27 (3), pp. 171 - 181 (2008)
The three-dimensional micro- and nanostructure of the aortic medial lamellar unit measured using 3D confocal and electron microscopy imaging. Matrix Biology
Journal Article
5 (9), pp. 797 - 804 (2008)
Single−spike detection in vitro and in vivo with a genetic Ca2+ sensor. Nature Methods 2007
Journal Article
5 (7), 185, pp. 1474 - 1493 (2007)
A dendrite-autonomous mechanism for direction selectivity in retinal starburst amacrine cells. PLoS Biology
Journal Article
24 (11), pp. 3517 - 3529 (2007)
Properties of coherence-gated wavefront sensing. Journal of the Optical Society of America A
Journal Article
102 (3), 034701, pp. 1 - 8 (2007)
Miniature random-access fiber scanner for in vivo multiphoton imaging. Journal of Applied Physics 2006
Journal Article
16 (5), pp. 562 - 570 (2006)
Towards neural circuit reconstruction with volume electron microscopy techniques. Current Opinion in Neurobiology
Journal Article
1 (2), pp. 648 - U5 (2006)
Two-photon targeted patching (TPTP) in vivo. Nature Protocols
Journal Article
9 (9), pp. 1125 - 1133 (2006)
Postsynaptic excitability is necessary for strengthening of cortical sensory responses during experience−dependent development. Nature Neuroscience
Journal Article
103 (46), pp. 17137 - 17142 (2006)
Adaptive wavefront correction in two−photon microscopy using coherence gated wavefront sensing. Proceedings of the National Academy of Sciences of the United States of America
Journal Article
49 (6), pp. 877 - 887 (2006)
Axons and synaptic boutons are highly dynamic in adult visual cortex. Neuron
Journal Article
23 (12), pp. 3139 - 3149 (2006)
On the fundamental imaging−depth limit in two−photon microsopy. Journal of the Optical Society of America A 2005
Journal Article
2 (12), pp. 932 - 940 (2005)
Deep tissue two-photon microscopy. Nature Methods