Publications of Markus Krumbholz

Journal Article (26)

2012
Journal Article
Colombo, E.; Cordiglieri, C.; Melli, G.; Newcombe, J.; Krumbholz, M.; Parada, L. F.; Medico, E.; Hohlfeld, R.; Meinl, E.; Farina, C.: Stimulation of the neurotrophin receptor TrkB on astrocytes drives nitric oxide production and neurodegeneration. Journal of Experimental Medicine 209 (3), pp. 521 - 535 (2012)
Journal Article
Eisele, S.; Krumbholz, M.; Fischer, M.-T.; Mohan, H.; Junker, A.; Arzberger, T.; Hohlfeld, R.; Bradl, M.; Lassmann, H.; Meinl, E.: Prospects of transcript profiling for mRNAs and microRNAs using formalin-fixed and paraffin-embedded dissected autoptic multiple sclerosis lesions. Brain Pathology 22 (5), pp. 607 - 618 (2012)
Journal Article
Krumbholz, M.; Derfuss, T.; Hohlfeld, R.; Meinl, E.: B cells and antibodies in multiple sclerosis pathogenesis and therapy. Nature Reviews Neurology 8 (11), pp. 613 - 623 (2012)
Journal Article
Schankin, C. J.; Reifferscheid, A. K.; Krumbholz, M.; Linn, J.; Rachinger, W.; Langer, S.; Sostak, P.; Arzberger, T.; Kretzschmar, H.; Straube, A.: Headache in patients with pituitary adenoma: Clinical and paraclinical findings. Cephalalgia 32 (16), pp. 1198 - 1207 (2012)
2011
Journal Article
Eisele, S.; Krumbholz, M.; Fischer, M.-T.; Mohan, H.; Junker, A.; Arzberger, T.; Hohlfeld, R.; Bradl, M.; Lassmann, H.; Meinl, E.: Prospects of transcript profiling for mRNAs and microRNAs using formalin fixed and paraffin embedded dissected autoptic multiple sclerosis lesions. Brain Pathology (accepted)
Journal Article
Meinl, E.; Derfuss, T.; Krumbholz, M.; Pröbstel, A. K.; Hohlfeld, R.: Humoral autoimmunity in multiple sclerosis. Journal of the Neurological Sciences 306 (1-2), pp. 180 - 182 (2011)
Journal Article
Pellkofer, H. L.; Krumbholz, M.; Berthele, A.; Hemmer, B.; Gerdes, L. A.; Havla, J.; Bittner, R.; Canis, M.; Meinl, E.; Hohlfeld, R. et al.; Kuempfel, T.: Long-term follow-up of patients with neuromyelitis optica after repeated therapy with rituximab. Neurology 76 (15), pp. 1310 - 1315 (2011)
Journal Article
Pröbstel, A.-K.; Dornmair, K.; Bittner, R.; Sperl, P.; Jenne, D. E.; Magalhaes, S.; Villalobos, A.; Breithaupt, C.; Weissert, R.; Jacob, U. et al.; Krumbholz, M.; Kuempfel, T.; Blaschek, A.; Stark, W.; Gaertner, J.; Pohl, D.; Rostasy, K.; Weber, F.; Forne, I.; Khademi, M.; Olsson, T.; Brilot, F.; Tantsis, E.; Dale, R. C.; Wekerle, H.; Hohlfeld, R.; Banwell, B.; Bar-Or, A.; Meinl, E.; Derfuss, T.: Antibodies to MOG are transient in childhood acute disseminated encephalomyelitis. Neurology 77 (6), pp. 580 - 588 (2011)
2010
Journal Article
Mohan, H.; Krumbholz, M.; Sharma, R.; Eisele, S.; Junker, A.; Sixt, M.; Newcombe, J.; Wekerle, H.; Hohlfeld, R.; Lassmann, H. et al.; Meinl, E.: Extracellular matrix in multiple sclerosis lesions: Fibrillar collagens, biglycan and decorin are upregulated and associated with infiltrating immune cells. Brain Pathology 20 (5), pp. 966 - 975 (2010)
Journal Article
Schankin, C. J.; Krumbholz, M.; Sostak, P.; Reinisch, V. M.; Goldbrunner, R.; Straube, A.: Headache in patients with a meningioma correlates with a bone-invasive growth pattern but not with cytokine expression. Cephalalgia 30 (4), pp. 413 - 424 (2010)
2009
Journal Article
Derfuss, T.; Parikh, K.; Velhin, S.; Braun, M.; Mathey, E.; Krumbholz, M.; Kümpfel, T.; Moldenhauer, A.; Rader, C.; Sonderegger, P. et al.; Pöllmann, W.; Tiefenthaller, C.; Bauer, J.; Lassmann, H.; Wekerle, H.; Karagogeos, D.; Hohlfeld, R.; Linington, C.; Meinl, E.: Contactin-2/TAG-1-directed autoimmunity is identified in multiple sclerosis patients and mediates gray matter pathology in animals. Proceedings of the National Academy of Sciences of the United States of America 106 (20), pp. 8302 - 8307 (2009)
Journal Article
Junker, A.; Krumbholz, M.; Eisele, S.; Mohan, H.; Augstein, F.; Bittner, R.; Lassmann, H.; Wekerle, H.; Hohlfeld, R.; Meinl, E.: MicroRNA profiling of multiple sclerosis lesions identifies modulators of the regulatory protein CD47. Brain 132, pp. 3342 - 3352 (2009)
Journal Article
Kessenbrock, K.; Krumbholz, M.; Schönermarck, U.; Back, W.; Gross, W. L.; Werb, Z.; Gröne, H. J.; Brinkmann, V.; Jenne, D. E.: Netting neutrophils in autoimmune small-vessel vasculitis. Nature Medicine 15 (6), pp. 623 - 625 (2009)
2008
Journal Article
Krumbholz, M.; Faber, H.; Steinmeyer, F.; Hoffmann, L. A.; Kümpfel, T.; Pellkofer, H.; Derfuss, T.; Ionescu, C.; Starck, M.; Hafner, C. et al.; Hohlfeld, R.; Meinl, E.: Interferon-beta increases BAFF levels in multiple sclerosis: implications for B cell autoimmunity. Brain 131, pp. 1455 - 1463 (2008)
Journal Article
Krumbholz, M.; Meinl, I.; Kümpfel, T.; Hohlfeld, R.; Meinl, E.: Natalizumab disproportionately increases circulating pre-B and B cells in multiple sclerosis. Neurology 71 (17), pp. 1350 - 1354 (2008)
Journal Article
Meinl, E.; Krumbholz, M.; Derfuss, T.; Junker, A.; Hohlfeld, R.: Compartmentalization of inflammation in the CNS: A major mechanism driving progressive multiple sclerosis. Journal of Neurological Sciences 274 (1-2), pp. 42 - 44 (2008)
2007
Journal Article
Hoffmann, L. A.; Krumbholz, M.; Faber, H.; Kuempfel, T.; Starck, M.; Pöllmann, W.; Meinl, E.; Hohlfeld, R.: Multiple sclerosis: relating MxA transcription to anti-interferon-beta-neutralizing antibodies. Neurology 68 (12), pp. 958 - 959 (2007)
Journal Article
Krumbholz, M.; Pellkofer, H.; Gold, R.; Hoffmann, L.; Hohlfeld, R.; Kümpfel, T.: Delayed allergic reaction to natalizumab associated with early formation of neutralizing antibodies. Archives of Neurology 64, pp. 1331 - 1333 (2007)
Journal Article
Krumbholz, M.; Theil, D.; Steinmeyer, F.; Cepok, S.; Hemmer, B.; Hofbauer, M.; Farina, C.; Derfuss, T.; Junker, A.; Arzberger, T. et al.; Sinicina, I.; Hartle, C.; Newcombe, J.; Hohlfeld, R.; Meinl, E.: CCL19 is constitutively expressed in the CNS, up-regulated in neuroinflammation, active and also inactive multiple sclerosis lesions. Journal of Neuroimmunology 190 (1-2), pp. 72 - 79 (2007)
2006
Journal Article
Krumbholz, M.; Theil, D.; Cepok, S.; Hemmer, B.; Kivisakk, P.; Ransohoff, R. M.; Hofbauer, M.; Farina, C.; Derfuss, T.; Hartle, C. et al.; Newcombe, J.; Hohlfeld, R.; Meinl, E.: Chemokines in multiple sclerosis: CXCL12 and CXCL13 up-regulation is differentially linked to CNS immune cell recruitment. Brain 129, pp. 200 - 211 (2006)
Journal Article
Meinl, E.; Krumbholz, M.; Hohlfeld, R.: B lineage cells in inflammatory central nervous system - Reply. Annals of Neurology 60 (4), p. 487 - 487 (2006)
Journal Article
Meinl, E.; Krumbholz, M.; Hohlfeld, R.: B lineage cells in the inflammatory central nervous system environment: Migration, maintenance, local antibody production, and therapeutic modulation. Annals of Neurology 59 (6), pp. 880 - 892 (2006)
2005
Journal Article
Farina, C.; Krumbholz, M.; Giese, T.; Hartmann, G.; Aloisi, F.; Meinl, E.: Preferential expression and function of Toll-like receptor 3 in human astrocytes. Journal of Neuroimmunology 159 (1-2), pp. 12 - 19 (2005)
Journal Article
Krumbholz, M.; Specks, U.; Wick, M.; Kalled, S. L.; Jenne, D. E.; Meinl, E.: BAFF is elevated in serum of patients with Wegener's granulomatosis. Journal of Autoimmunity 25 (4), pp. 298 - 302 (2005)
Journal Article
Krumbholz, M.; Theil, D.; Derfuss, T.; Rosenwald, A.; Schrader, F.; Monoranu, C. M.; Kalled, S. L.; Hess, D. M.; Serafini, B.; Aloisi, F. et al.; Wekerle, H.; Hohlfeld, R.; Meinl, E.: BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma. Journal of Experimental Medicine 201 (2), pp. 195 - 200 (2005)
Journal Article
Vargas-Leal, V.; Bruno, R.; Derfuss, T.; Krumbholz, M.; Hohlfeld, R.; Meinl, E.: Expression and function of glial cell line-derived neurotrophic factor (GDNF) family ligands and their receptors on human immune cells. Journal of Immunology 175 (4), pp. 2301 - 2308 (2005)
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