Publikationen von Edgar Meinl

Zeitschriftenartikel (58)

2012
Zeitschriftenartikel
Colombo, E.; Cordiglieri, C.; Melli, G.; Newcombe, J.; Krumbholz, M.; Parada, L. F.; Medico, E.; Hohlfeld, R.; Meinl, E.; Farina, C.: Stimulation of the neurotrophin receptor TrkB on astrocytes drives nitric oxide production and neurodegeneration. Journal of Experimental Medicine 209 (3), S. 521 - 535 (2012)
Zeitschriftenartikel
Derfuss, T.; Meinl, E.: Identifying autoantigens in demyelinating diseases: Valuable clues to diagnosis and treatment? Current Opinion in Neurology 25 (3), S. 231 - 238 (2012)
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Eisele, S.; Krumbholz, M.; Fischer, M.-T.; Mohan, H.; Junker, A.; Arzberger, T.; Hohlfeld, R.; Bradl, M.; Lassmann, H.; Meinl, E.: Prospects of transcript profiling for mRNAs and microRNAs using formalin-fixed and paraffin-embedded dissected autoptic multiple sclerosis lesions. Brain Pathology 22 (5), S. 607 - 618 (2012)
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Elliott, C.; Lindner, M.; Arthur, A.; Brennan, K.; Jarius, S.; Hussey, J.; Chan, A.; Stroet, A.; Olsson, T.; Willison, H. et al.; Barnett, S. C.; Meinl, E.; Linington, C.: Functional identification of pathogenic autoantibody responses in patients with multiple sclerosis. Brain 135, S. 1819 - 1833 (2012)
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Krumbholz, M.; Derfuss, T.; Hohlfeld, R.; Meinl, E.: B cells and antibodies in multiple sclerosis pathogenesis and therapy. Nature Reviews Neurology 8 (11), S. 613 - 623 (2012)
Zeitschriftenartikel
Mayer, M. C.; Hohlfeld, R.; Meinl, E.: Viability of autoantibody-targets: How to tackle pathogenetic heterogeneity as an obstacle for treatment of multiple sclerosis. JOURNAL OF THE NEUROLOGICAL SCIENCES 319 (1-2), S. 2 - 7 (2012)
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Mayer, M. C.; Meinl, E.: Glycoproteins as targets of autoantibodies in CNS inflammation: MOG and more. Therapeutic Advances in Neurological Disorders 5 (3), S. 147 - 159 (2012)
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Meinl, E.; Meister, G.: MicroRNAs in the CSF Macro-advance in MS? Neurology 79 (22), S. 2162 - 2163 (2012)
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Ng, J. K. M.; Malotka, J.; Kawakami, N.; Derfuss, T.; Khademi, M.; Olsson, T.; Linington, C.; Odaka, M.; Tackenberg, B.; Pruess, H. et al.; Schwab, J. M.; Harms, L.; Harms, H.; Sommer, C.; Rasband, M. N.; Eshed-Eisenbach, Y.; Peles, E.; Hohlfeld, R.; Yuki, N.; Dornmair, K.; Meinl, E.: Neurofascin as a target for autoantibodies in peripheral neuropathies. Neurology 79 (23), S. 2241 - 2248 (2012)
2011
Zeitschriftenartikel
Eisele, S.; Krumbholz, M.; Fischer, M.-T.; Mohan, H.; Junker, A.; Arzberger, T.; Hohlfeld, R.; Bradl, M.; Lassmann, H.; Meinl, E.: Prospects of transcript profiling for mRNAs and microRNAs using formalin fixed and paraffin embedded dissected autoptic multiple sclerosis lesions. Brain Pathology (angenommen)
Zeitschriftenartikel
Held, K.; Junker, A.; Dornmair, K.; Meinl, E.; Sinicina, I.; Brandt, T.; Theil, D.; Derfuss, T.: Expression of herpes simplex virus 1-encoded microRNAs in human trigeminal ganglia and their relation to local T-cell infiltrates. Journal of Virology 85 (19), S. 9680 - 9685 (2011)
Zeitschriftenartikel
Junker, A.; Hohlfeld, R.; Meinl, E.: The emerging role of microRNAs in multiple sclerosis. Nature Reviews Neurology 7 (1), S. 56 - 59 (2011)
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Meinl, E.: Untapped targets in multiple sclerosis. JOURNAL OF THE NEUROLOGICAL SCIENCES 311 (Suppl. 1), S. S12 - S15 (2011)
Zeitschriftenartikel
Meinl, E.; Derfuss, T.; Krumbholz, M.; Pröbstel, A. K.; Hohlfeld, R.: Humoral autoimmunity in multiple sclerosis. Journal of the Neurological Sciences 306 (1-2), S. 180 - 182 (2011)
Zeitschriftenartikel
Pellkofer, H. L.; Krumbholz, M.; Berthele, A.; Hemmer, B.; Gerdes, L. A.; Havla, J.; Bittner, R.; Canis, M.; Meinl, E.; Hohlfeld, R. et al.; Kuempfel, T.: Long-term follow-up of patients with neuromyelitis optica after repeated therapy with rituximab. Neurology 76 (15), S. 1310 - 1315 (2011)
Zeitschriftenartikel
Pröbstel, A.-K.; Dornmair, K.; Bittner, R.; Sperl, P.; Jenne, D. E.; Magalhaes, S.; Villalobos, A.; Breithaupt, C.; Weissert, R.; Jacob, U. et al.; Krumbholz, M.; Kuempfel, T.; Blaschek, A.; Stark, W.; Gaertner, J.; Pohl, D.; Rostasy, K.; Weber, F.; Forne, I.; Khademi, M.; Olsson, T.; Brilot, F.; Tantsis, E.; Dale, R. C.; Wekerle, H.; Hohlfeld, R.; Banwell, B.; Bar-Or, A.; Meinl, E.; Derfuss, T.: Antibodies to MOG are transient in childhood acute disseminated encephalomyelitis. Neurology 77 (6), S. 580 - 588 (2011)
2010
Zeitschriftenartikel
Derfuss, T.; Linington, C.; Hohlfeld, R.; Meinl, E.: Axo-glial antigens as targets in multiple sclerosis: implications for axonal and grey matter injury. Journal of Molecular Medicine 88 (8), S. 753 - 761 (2010)
Zeitschriftenartikel
Meinl, E.; Derfuss, T.; Linington, C.: Identifying targets for autoantibodies in CNS inflammation: Strategies and achievements. Clinical and Experimental Neuroimmunology 1 (2), S. 47 - 60 (2010)
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Mohan, H.; Krumbholz, M.; Sharma, R.; Eisele, S.; Junker, A.; Sixt, M.; Newcombe, J.; Wekerle, H.; Hohlfeld, R.; Lassmann, H. et al.; Meinl, E.: Extracellular matrix in multiple sclerosis lesions: Fibrillar collagens, biglycan and decorin are upregulated and associated with infiltrating immune cells. Brain Pathology 20 (5), S. 966 - 975 (2010)
2009
Zeitschriftenartikel
Derfuss, T.; Parikh, K.; Velhin, S.; Braun, M.; Mathey, E.; Krumbholz, M.; Kümpfel, T.; Moldenhauer, A.; Rader, C.; Sonderegger, P. et al.; Pöllmann, W.; Tiefenthaller, C.; Bauer, J.; Lassmann, H.; Wekerle, H.; Karagogeos, D.; Hohlfeld, R.; Linington, C.; Meinl, E.: Contactin-2/TAG-1-directed autoimmunity is identified in multiple sclerosis patients and mediates gray matter pathology in animals. Proceedings of the National Academy of Sciences of the United States of America 106 (20), S. 8302 - 8307 (2009)
Zeitschriftenartikel
Dornmair, K.; Meinl, E.; Hohlfeld, R.: Novel approaches for identifying target antigens of autoreactive human B and T cells. Seminars in Immunopathology 31 (4), S. 467 - 477 (2009)
Zeitschriftenartikel
Junker, A.; Krumbholz, M.; Eisele, S.; Mohan, H.; Augstein, F.; Bittner, R.; Lassmann, H.; Wekerle, H.; Hohlfeld, R.; Meinl, E.: MicroRNA profiling of multiple sclerosis lesions identifies modulators of the regulatory protein CD47. Brain 132, S. 3342 - 3352 (2009)
Zeitschriftenartikel
Kerschensteiner, M.; Meinl, E.; Hohlfeld, R.: Neuro-immune crosstalk in CNS. Neuroscience 158 (3), S. 1122 - 1132 (2009)
2008
Zeitschriftenartikel
Berzi, A.; Ayata, C. K.; Cavalcante, P.; Falcone, C.; Candiago, E.; Motta, T.; Bernasconi, P.; Hohlfeld, R.; Mantegazza, R.; Meinl, E. et al.; Farina, C.: BDNF and its receptors in human myasthenic thymus: Implications for cell fate in thymic pathology. Journal of Neuroimmunology 197 (2), S. 128 - 139 (2008)
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Derfuss, T.; Direskeneli, G. S.; Hohlfeld, R.; Meinl, E.: Autoantigen- und erregerspezifische T- und B-Zellreaktionen bei multipler Sklerose: „Eine unendliche Geschichte”? Aktuelle Neurologie 35 (7), S. 345 - 355 (2008)
Zeitschriftenartikel
Hohlfeld, R.; Meinl, E.; Dornmair, K.: B- and T-cell responses in multiple sclerosis: Novel approaches offer new insights. Journal of Neurological Sciences 274 (1-2), S. 5 - 8 (2008)
Zeitschriftenartikel
Krumbholz, M.; Faber, H.; Steinmeyer, F.; Hoffmann, L. A.; Kümpfel, T.; Pellkofer, H.; Derfuss, T.; Ionescu, C.; Starck, M.; Hafner, C. et al.; Hohlfeld, R.; Meinl, E.: Interferon-beta increases BAFF levels in multiple sclerosis: implications for B cell autoimmunity. Brain 131, S. 1455 - 1463 (2008)
Zeitschriftenartikel
Krumbholz, M.; Meinl, I.; Kümpfel, T.; Hohlfeld, R.; Meinl, E.: Natalizumab disproportionately increases circulating pre-B and B cells in multiple sclerosis. Neurology 71 (17), S. 1350 - 1354 (2008)
Zeitschriftenartikel
Kuhl, A.; Melberg, A.; Meinl, E.; Nürnberg, G.; Nürnberg, P.; Kehrer-Sawatzki, H.; Jenne, D. E.: Myofibrillar myopathy with arrhythmogenic right ventricular cardiomyopathy 7: corroboration and narrowing of the critical region on 10q22.3. European Journal of Human Genetics 16, S. 367 - 373 (2008)
Zeitschriftenartikel
Meinl, E.; Krumbholz, M.; Derfuss, T.; Junker, A.; Hohlfeld, R.: Compartmentalization of inflammation in the CNS: A major mechanism driving progressive multiple sclerosis. Journal of Neurological Sciences 274 (1-2), S. 42 - 44 (2008)
2007
Zeitschriftenartikel
Derfuss, T.; Segerer, S.; Herberger, S.; Sinicina, I.; Hufner, K.; Ebelt, K.; Knaus, H. G.; Steiner, I.; Meinl, E.; Dornmair, K. et al.; Arbusow, V.; Strupp, M.; Brandt, T.; Theil, D.: Presence of HSV-1 immediate early genes and clonally expanded T-cells with a memory effector phenotype in human trigeminal ganglia. Brain Pathology 17 (4), S. 389 - 398 (2007)
Zeitschriftenartikel
Farina, C.; Aloisi, F.; Meinl, E.: Astrocytes are active players in cerebral innate immunity. Trends in Immunology 28 (3), S. 138 - 145 (2007)
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Hoffmann, L. A.; Krumbholz, M.; Faber, H.; Kuempfel, T.; Starck, M.; Pöllmann, W.; Meinl, E.; Hohlfeld, R.: Multiple sclerosis: relating MxA transcription to anti-interferon-beta-neutralizing antibodies. Neurology 68 (12), S. 958 - 959 (2007)
Zeitschriftenartikel
Hohlfeld, R.; Kerschensteiner, M.; Meinl, E.: Dual role of inflammation in CNS disease. Neurology 68 (3), S. 58 - 63 (2007)
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Junker, A.; Ivanidze, J.; Malotka, J.; Eiglmeier, I.; Lassmann, H.; Wekerle, H.; Meinl, E.; Hohlfeld, R.; Dornmair, K.: Multiple sclerosis: T-cell receptor expression in distinct brain regions. Brain 130, S. 2789 - 2799 (2007)
Zeitschriftenartikel
Krumbholz, M.; Theil, D.; Steinmeyer, F.; Cepok, S.; Hemmer, B.; Hofbauer, M.; Farina, C.; Derfuss, T.; Junker, A.; Arzberger, T. et al.; Sinicina, I.; Hartle, C.; Newcombe, J.; Hohlfeld, R.; Meinl, E.: CCL19 is constitutively expressed in the CNS, up-regulated in neuroinflammation, active and also inactive multiple sclerosis lesions. Journal of Neuroimmunology 190 (1-2), S. 72 - 79 (2007)
Zeitschriftenartikel
Mathey, E. K.; Derfuss, T.; Storch, M. K.; Williams, K. R.; Hales, K.; Woolley, D. R.; Al-Hayani, A.; Davies, S. N.; Rasband, M. N.; Olsson, T. et al.; Moldenhauer, A.; Velhin, S.; Hohlfeld, R.; Meinl, E.; Linington, C.: Neurofascin as a novel target for autoantibody-mediated axonal injury. Journal of Experimental Medicine 204 (10), S. 2363 - 2372 (2007)
2006
Zeitschriftenartikel
Krumbholz, M.; Theil, D.; Cepok, S.; Hemmer, B.; Kivisakk, P.; Ransohoff, R. M.; Hofbauer, M.; Farina, C.; Derfuss, T.; Hartle, C. et al.; Newcombe, J.; Hohlfeld, R.; Meinl, E.: Chemokines in multiple sclerosis: CXCL12 and CXCL13 up-regulation is differentially linked to CNS immune cell recruitment. Brain 129, S. 200 - 211 (2006)
Zeitschriftenartikel
Meinl, E.; Krumbholz, M.; Hohlfeld, R.: B lineage cells in inflammatory central nervous system - Reply. Annals of Neurology 60 (4), S. 487 - 487 (2006)
Zeitschriftenartikel
Meinl, E.; Krumbholz, M.; Hohlfeld, R.: B lineage cells in the inflammatory central nervous system environment: Migration, maintenance, local antibody production, and therapeutic modulation. Annals of Neurology 59 (6), S. 880 - 892 (2006)
2005
Zeitschriftenartikel
Derfuss, T.; Hohlfeld, R.; Meinl, E.: Intrathecal antibody (IgG) production against human herpesvirus type 6 occurs in about 20% of multiple sclerosis patients and might be linked to a polyspecific B-cell response. Journal of Neurology 252 (8), S. 968 - 971 (2005)
Zeitschriftenartikel
Farina, C.; Krumbholz, M.; Giese, T.; Hartmann, G.; Aloisi, F.; Meinl, E.: Preferential expression and function of Toll-like receptor 3 in human astrocytes. Journal of Neuroimmunology 159 (1-2), S. 12 - 19 (2005)
Zeitschriftenartikel
Farina, C.; Weber, M. S.; Meinl, E.; Wekerle, H.; Hohlfeld, R.: Glatiramer acetate in multiple sclerosis: update on potential mechanisms of action. Lancet Neurology 4 (9), S. 567 - 575 (2005)
Zeitschriftenartikel
Krumbholz, M.; Specks, U.; Wick, M.; Kalled, S. L.; Jenne, D. E.; Meinl, E.: BAFF is elevated in serum of patients with Wegener's granulomatosis. Journal of Autoimmunity 25 (4), S. 298 - 302 (2005)
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Krumbholz, M.; Theil, D.; Derfuss, T.; Rosenwald, A.; Schrader, F.; Monoranu, C. M.; Kalled, S. L.; Hess, D. M.; Serafini, B.; Aloisi, F. et al.; Wekerle, H.; Hohlfeld, R.; Meinl, E.: BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma. Journal of Experimental Medicine 201 (2), S. 195 - 200 (2005)
Zeitschriftenartikel
Theil, D.; Farina, C.; Meinl, E.: Differential expression of CD150 (SLAM) on monocytes and macrophages in chronic inflammatory contexts: abundant in Crohn's disease, but not in multiple sclerosis. Journal of Clinical Pathology 58 (1), S. 110 - 111 (2005)
Zeitschriftenartikel
Vargas-Leal, V.; Bruno, R.; Derfuss, T.; Krumbholz, M.; Hohlfeld, R.; Meinl, E.: Expression and function of glial cell line-derived neurotrophic factor (GDNF) family ligands and their receptors on human immune cells. Journal of Immunology 175 (4), S. 2301 - 2308 (2005)
2004
Zeitschriftenartikel
Farina, C.; Theil, D.; Semlinger, B.; Hohlfeld, R.; Meinl, E.: Distinct responses of monocytes to Toll-like receptor ligands and inflammatory cytokines. International Immunology 16 (6), S. 799 - 809 (2004)
Zeitschriftenartikel
Meinl, E.; Voltz, R.: Biomarker in der Therapie der Multiplen Sklerose: Läßt sich der Erfolg bald vorhersagen? MMW-Fortschr. Med. Sonderheft 2, S. 517 - 517 (2004)
Zeitschriftenartikel
Weber, M. S.; Starck, M.; Wagenpfeil, S.; Meinl, E.; Hohlfeld, R.; Farina, C.: Multiple sclerosis: glatiramer acetate inhibits monocyte reactivity in vitro and in vivo. Brain 127, S. 1370 - 1378 (2004)
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