Gezeichnetes Bild mit einer Personengruppe, die vor Bäumen und einem Gebäude steht. Die Personengruppe beinhaltet Kinder, Frauen, Männer und eine schwangere Person. Im Hintergrund spielen zwei Personen Ball und eine Person fährt Fahrrad.

Publikationen von Dieter E. Jenne

Zeitschriftenartikel (82)

2023
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Casal Moura, M.; Thompson, G. E.; Nelson, D. R.; Fussner, L. A.; Hummel, A. M.; Jenne, D. E.; Emerling, D.; Fervenza, F. C.; Kallenberg, C. G. M.; Langford, C. A. et al.; McCune, W. J.; Merkel, P. A.; Monach, P. A.; Seo, P.; Spiera, R. F.; St. Clair, E. W.; Ytterberg, S. R.; Stone, J. H.; Robinson, W. H.; Specks, U.: Activation of a latent epitope causing differential binding of anti-neutrophil cytoplasmic antibodies to proteinase 3. Arthritis and Rheumatology 75 (5), S. 748 - 759 (2023)
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Guarino, C.; Seren, S.; Lemoine, R.; Hummel, A. M.; Margotin, J.-E.; El-Benna, J.; Hoarau, C.; Specks, U.; Jenne, D. E.; Korkmaz, B.: Constitutive and induced forms of membrane-bound proteinase 3 interact with antineutrophil cytoplasmic antibodies and promote immune activation of neutrophils. The Journal of Biological Chemistry 299 (4), 103072 (2023)
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Janakiraman, M.; Leliavski, A.; Varadarajulu, J.; Jenne, D. E.; Krishnamoorthy, G.: An engineered Fc fusion protein that targets antigen-specific T cells and autoantibodies mitigates autoimmune disease. Journal of Neuroinflammation 20, 291 (2023)
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Spella, M.; Ntaliarda, G.; Skiadas, G.; Lamort, A.-S.; Vreka, M.; Marazioti, A.; Lilis, I.; Bouloukou, E.; Giotopoulou, G. A.; Pepe, M. A. A. et al.; Weiss, S. A. I.; Petrera, A.; Hauck, S. M.; Koch, I.; Lindner, M.; Hatz, R. A.; Behr, J.; Arendt, K. A. M.; Giopanou, I.; Brunn, D.; Savai, R.; Jenne, D. E.; de Chateau, M.; Yull, F. E.; Blackwell, T. S.; Stathopoulos, G. T.: Non-oncogene addiction of KRAS-mutant cancers to IL-1beta via versican and mononuclear IKKbeta. Cancers / Molecular Diversity Preservation International (MDPI) 15 (6), 1866 (2023)
2022
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Ebert, M.; Jerke, U.; Eulenberg-Gustavus, C.; Kling, L.; Jenne, D. E.; Kirchner, M.; Mertins, P.; Bieringer, M.; Elitok, S.; Eckardt, K.-U. et al.; Schreiber, A.; Salama, A. D.; Kettritz, R.: Protective alpha1-antitrypsin effects in autoimmune vasculitis are compromised by methionine oxidation. The Journal of Clinical Investigation 132 (23), e160089 (2022)
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Kessler, N.; Viehmann, S. F.; Krollmann, C.; Mai, K.; Kirschner, K. M.; Luksch, H.; Kotagiri, P.; Böhner, A. M. C.; Huugen, D.; de Oliveira Mann, C. C. et al.; Otten, S.; Weiss, S. A. I.; Zillinger, T.; Dobrikova, K.; Jenne, D. E.; Behrendt, R.; Ablasser, A.; Bartok, E.; Hartmann, G.; Hopfner, K.-P.; Lyons, P. A.; Boor, P.; Rösen-Wolff, A.; Teichmann, L. L.; Heeringa, P.; Kurts, C.; Garbi, N.: Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing. The Journal of experimental medicine 219 (10), e20220759 (2022)
2021
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Morrone, C.; Smirnova, N. F.; Jeridi, A.; Kneidinger, N.; Hollauer, C.; Schupp, J. C.; Kaminski, N.; Jenne, D. E.; Eickelberg, O.; Yildirim, A. O.: Cathepsin B promotes collagen biosynthesis, which drives bronchiolitis obliterans syndrome. European Respiratory Journal 57 (5), 2001416 (2021)
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Schoeps, B.; Eckfeld, C.; Prokopchuk, O.; Boettcher, J.; Haeussler, D.; Steiger, K.; Demir, I. E.; Knolle, P.; Soehnlein, O.; Jenne, D. E. et al.; Hermann, C. D.; Krueger, A.: TIMP1 triggers neutrophil extracellular trap formation in pancreatic cancer. Cancer Research 81 (13), S. 3568 - 3579 (2021)
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Seren, S.; Derian, L.; Keles, I.; Guillon, A.; Lesner, A.; Gonzalez, L.; Baranek, T.; Si-Tahar, M.; Marchand-Adam, S.; Jenne, D. E. et al.; Paget, C.; Jouan, Y.; Korkmaz, B.: Proteinase release from activated neutrophils in mechanically ventilated patients with non-COVID-19 and COVID-19 pneumonia. European Respiratory Journal 57 (4), 2003755 (2021)
2020
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Korkmaz, B.; Lesner, A.; Marchand-Adam, S.; Moss, C.; Jenne, D. E.: Lung protection by cathepsin C inhibition: A new hope for COVID-19 and ARDS? Journal of Medicinal Chemistry 63 (22), S. 13258 - 13265 (2020)
2019
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Fernandez, I. M.; Macrini, C.; Krumbholz, M.; Hensbergen, P. J.; Ederveen, A. L. H.; Winklmeier, S.; Vural, A.; Kurne, A.; Jenne, D. E.; Kamp, F. et al.; Gerdes, L. A.; Hohlfeld, R.; Wuhrer, M.; Kümpfel, T.; Meinl, E.: The glycosylation site of myelin oligodendrocyte glycoprotein affects autoantibody recognition in a large proportion of patients. Frontiers in immunology 10, 1189 (2019)
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Korkmaz, B.; Lesner, A.; Wysocka, M.; Gieldon, A.; Hakansson, M.; Gauthier, F.; Logan, D. T.; Jenne, D. E.; Lauritzen, C.; Pedersen, J.: Structure-based design and in vivo anti-arthritic activity evaluation of a potent dipeptidyl cyclopropyl nitrile inhibitor of cathepsin C. Biochemical Pharmacology 164, S. 349 - 367 (2019)
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Lamort, A.-S.; Hamon, Y.; Czaplewski, C.; Gieldon, A.; Seren, S.; Coquet, L.; Lecaille, F.; Lesner, A.; Lalmanach, G.; Gauthier, F. et al.; Jenne, D. E.; Korkmaz, B.: Processing and maturation of cathepsin C zymogen: A biochemical and molecular modeling analysis. International Journal of Molecular Sciences 20 (19), 4747 (2019)
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Rehm, S. R. T.; Smirnova, N. F.; Morrone, C.; Goetzfried, J.; Feuchtinger, A.; Pedersen, J.; Korkmaz, B.; Yildirim, A. O.; Jenne, D. E.: Premedication with a cathepsin C inhibitor alleviates early primary graft dysfunction in mouse recipients after lung transplantation. Scientific Reports 9, 9925 (2019)
2018
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Goetzfried, J.; Smirnova, N. F.; Morrone, C.; Korkmaz, B.; Yildirim, A. O.; Eickelberg, O.; Jenne, D. E.: Preservation with α1-antitrypsin improves primary graft function of murine lung transplants. The Journal of Heart and Lung Transplantation 37 (8), S. 1021 - 1028 (2018)
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Guarino, C.; Gruba, N.; Grzywa, R.; Dyguda-Kazimierowicz, E.; Hamon, Y.; Legowska, M.; Skorenski, M.; Dallet-Choisy, S.; Marchand-Adam, S.; Kellenberger, C. et al.; Jenne, D. E.; Sienczyk, M.; Lesner, A.; Gauthier, F.; Korkmaz, B.: Exploiting the S4-S5 specificity of human neutrophil proteinase 3 to improve the potency of deptidyl Di(chlorophenyl)-phosphonate ester inhibitors: A kinetic and molecular modeling analysis. Journal of Medicinal Chemistry 61 (5), S. 1858 - 1870 (2018)
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Seren, S.; Abouzaid, M. R.; Eulenberg-Gustavus, C.; Hirschfeld, J.; Soliman, H. N.; Jerke, U.; N'Guessan, K.; Dallet-Choisy, S.; Lesner, A.; Lauritzen, C. et al.; Schacher, B.; Eickholz, P.; Nagy, N.; Szell, M.; Croix, C.; Viaud-Massuard, M.-C.; Aldosari, A. A. F.; Ragunatha, S.; Mostafa, M. I.; Giampieri, F.; Battino, M.; Cornillier, H.; Lorette, G.; Stephan, J.-L.; Goizet, C.; Pedersen, J.; Gauthier, F.; Jenne, D. E.; Marchand-Adam, S.; Chapple, I. L.; Kettritz, R.; Korkmaz, B.: Consequences of cathepsin C inactivation for membrane exposure of proteinase 3, the target antigen in autoimmune vasculitis. The Journal of Biological Chemistry 293 (32), S. 12415 - 12428 (2018)
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Spadaro, M.; Winklmeier, S.; Beltran, E.; Macrini, C.; Hoeftberger, R.; Schuh, E.; Thaler, F. S.; Gerdes, L. A.; Laurent, S.; Gerhards, R. et al.; Braendle, S.; Dornmair, K.; Breithaupt, C.; Krumbholz, M.; Moser, M.; Krishnamoorthy, G.; Kamp, F.; Jenne, D. E.; Hohlfeld, R.; Kuempfel, T.; Lassmann, H.; Kawakami, N.; Meinl, E.: Pathogenicity of human antibodies against myelin oligodendrocyte glycoprotein. Annals of Neurology 84 (2), S. 315 - 328 (2018)
2017
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Guarino, C.; Hamon, Y.; Croix, C.; Lamort, A.-S.; Dallet-Choisy, S.; Marchand-Adam, S.; Lesner, A.; Baranek, T.; Viaud-Massuard, M.-C.; Lauritzen, C. et al.; Pedersen, J.; Heuze-Vourc'h, N.; Si-Tahar, M.; Firatli, E.; Jenne, D. E.; Gauthier, F.; Horwitz, M. S.; Borregaard, N.; Korkmaz, B.: Prolonged pharmacological inhibition of cathepsin C results in elimination of neutrophil serine proteases. Biochemical Pharmacology 131, S. 52 - 67 (2017)
2016
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Dau, T.; Edeleva, E. V.; Seidel, S. A. I.; Stockley, R. A.; Braun, D.; Jenne, D. E.: Quantitative analysis of protease recognition by inhibitors in plasma using microscale thermophoresis. Scientific Reports 6, 35413 (2016)
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Hamon, Y.; Legowska, M.; Fergelot, P.; Dallet-Choisy, S.; Newell, L.; Vanderlynden, L.; Valeshabad, A. K.; Acrich, K.; Kord, H.; Charalampos, T. et al.; Morice-Picard, F.; Surplice, I.; Zoidakis, J.; David, K.; Vlahou, A.; Ragunatha, S.; Nagy, N.; Farkas, K.; Szell, M.; Goizet, C.; Schacher, B.; Battino, M.; Aldosari, A. A. F.; Wang, X.; Liu, Y.; Marchand-Adam, S.; Lesner, A.; Kara, E.; Korkmaz-Icoez, S.; Moss, C.; Eickholz, P.; Taieb, A.; Kavukcu, S.; Jenne, D. E.; Gauthier, F.; Korkmaz, B.: Analysis of urinary cathepsin C for diagnosing Papillon-Lefevre syndrome. The FEBS Journal 283 (3), S. 498 - 509 (2016)
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Hamon, Y.; Legowska, M.; Herve, V.; Dallet-Choisy, S.; Marchand-Adam, S.; Vanderlynden, L.; Demonte, M.; Williams, R.; Scott, C. J.; Si-Tahar, M. et al.; Heuze-Vourc'h, N.; Lalmanach, G.; Jenne, D. E.; Lesner, A.; Gauthier, F.; Korkmaz, B.: Neutrophilic cathepsin C is maturated by a multistep proteolytic process and secreted by activated cells during inflammatory lung diseases. The Journal of Biological Chemistry 291 (16), S. 8486 - 8499 (2016)
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Korkmaz, B.; Lesner, A.; Guarino, C.; Wysocka, M.; Kellenberger, C.; Watier, H.; Specks, U.; Gauthier, F.; Jenne, D. E.: Inhibitors and antibody fragments as potential anti-inflammatory therapeutics targeting neutrophil proteinase 3 in human disease. Pharmacological Reviews 68 (3), S. 603 - 630 (2016)
2015
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Dau, T.; Sarker, R. S. J.; Yildirim, A. O.; Eickelberg, O.; Jenne, D. E.: Autoprocessing of neutrophil elastase near its active site reduces the efficiency of natural and synthetic elastase inhibitors. Nature Communications 6, 6722 (2015)
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Hinkofer, L. C.; Hummel, A. M.; Stone, J. H.; Hoffman, G. S.; Merkel, P. A.; Spiera, E. R. F.; Clair, W. S.; McCune, J. W.; Davis, J. C.; Specks, U. et al.; Jenne, D. E.: Allosteric modulation of proteinase 3 activity by anti-neutrophil cytoplasmic antibodies in granulomatosis with polyangiitis. Journal of Autoimmunity 59, S. 43 - 52 (2015)
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Laurent, S. A.; Hoffmann, F. S.; Kuhn, P.-H.; Cheng, Q.; Chu, Y.; Schmidt-Supprian, M.; Hauck, S. M.; Schuh, E.; Krumbholz, M.; Rübsamen, H. et al.; Wanngren, J.; Khademi, M.; Olsson, T.; Alexander, T.; Hiepe, F.; Pfister, H.-W.; Weber, F.; Jenne, D. E.; Wekerle, H.; Hohlfeld, R.; Lichtenthaler, S. F.; Meinl, E.: γ-secretase directly sheds the survival receptor BCMA from plasma cells. Nature Communications 6, 7333 (2015)
2014
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Guarino, C.; Legowska, M.; Epinette, C.; Kellenberger, C.; Dallet-Choisy, S.; Sienczyk, M.; Gabant, G.; Cadene, M.; Zoidakis, J.; Vlahou, A. et al.; Wysocka, M.; Marchand-Adam, S.; Jenne, D. E.; Lesner, A.; Gauthier, F.; Korkmaz, B.: New selective peptidyl Di(chlorophenyl) phosphonate esters for visualizing and blocking neutrophil proteinase 3 in human diseases. The Journal of Biological Chemistry 289 (46), S. 31777 - 31791 (2014)
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Guyot, N.; Wartelle, J.; Malleret, L.; Todorov, A. A.; Devouassoux, G.; Pacheco, Y.; Jenne, D. E.; Belaaouaj, A.: Unopposed cathepsin G, neutrophil elastase, and proteinase 3 cause severe lung damage and emphysema. American Journal of Pathology 184 (8), S. 2197 - 2210 (2014)
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Jenne, D. E.: Off-target rewards of augmentation therapy with α1-antitrypsin. American Journal of Respiratory and Critical Care Medicine 190 (11), S. 1203 - 1204 (2014)
2013
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Hedberg, C.; Melberg, A.; Kuhl, A.; Jenne, D. E.; Oldfors, A.: Functional characterization of desmin mutant p.P419S Reply [Letter]. European journal of human genetics 21 (6), S. 590 - 590 (2013)
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Hinkofer, L. C.; Seidel, S. A. I.; Korkmaz, B.; Silva, F.; Hummel, A. M.; Braun, D.; Jenne, D. E.; Specks, U.: A monoclonal antibody (MCPR3-7) interfering with the activity of proteinase 3 by an allosteric mechanism. The Journal of Biological Chemistry 288 (37), S. 26635 - 26648 (2013)
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Mayer, M. C.; Breithaupt, C.; Reindl, M.; Schanda, K.; Rostasy, K.; Berger, T.; Dale, R. C.; Brilot, F.; Olsson, T.; Jenne, D. E. et al.; Proebstel, A.-K.; Dornmair, K.; Wekerle, H.; Hohlfeld, R.; Banwell, B.; Bar-Or, A.; Meinl, E.: Distinction and temporal stability of conformational epitopes on myelin oligodendrocyte glycoprotein recognized by patients with different inflammatory central nervous system diseases. Journal of Immunology 191 (7), S. 3594 - 3604 (2013)
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Molnarfi, N.; Schulze-Topphoff, U.; Weber, M. S.; Patarroyo, J. C.; Prod'homme, T.; Varrin-Doyer, M.; Shetty, A.; Linington, C.; Slavin, A. J.; Hidalgo, J. et al.; Jenne, D. E.; Wekerle, H.; Sobel, R. A.; Bernard, C. C. A.; Shlomchik, M. J.; Zamvil, S. S.: MHC class II-dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies. Journal of Experimental Medicine 210 (13), S. 2921 - 2937 (2013)
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O'Donoghue, A. J.; Jin, Y.; Knudsen, G. M.; Perera, N. C.; Jenne, D. E.; Murphy, J. E.; Craik, C. S.; Hermiston, T. W.: Global substrate profiling of proteases in human neutrophil extracellular traps reveals consensus motif predominantly contributed by elastase. PLoS One 8 (9), e75141 (2013)
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Perera, N. C.; Wiesmueller, K.-H.; Larsen, M. T.; Schacher, B.; Eickholz, P.; Borregaard, N.; Jenne, D. E.: NSP4 is stored in azurophil granules and released by activated neutrophils as active endoprotease with restricted specificity. Journal of Immunology 191 (5), S. 2700 - 2707 (2013)
2012
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Hedberg, C.; Melberg, A.; Kuhl, A.; Jenne, D. E.; Oldfors, A.: Autosomal dominant myofibrillar myopathy with arrhythmogenic right ventricular cardiomyopathy 7 is caused by a DES mutation. European journal of human genetics 20 (9), S. 984 - 985 (2012)
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Lippok, S.; Seidel, S. A. I.; Duhr, S.; Uhland, K.; Holthoff, H.-P.; Jenne, D. E.; Braun, D.: Direct detection of antibody concentration and affinity in human serum using microscale thermophoresis. Analytical Chemistry 84 (8), S. 3523 - 3530 (2012)
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Mankan, A. K.; Dau, T.; Jenne, D. E.; Hornung, V.: The NLRP3/ASC/Caspase-1 axis regulates IL-1 ss processing in neutrophils. European Journal of Immunology 42 (3), S. 710 - 715 (2012)
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Perera, N. C.; Jenne, D. E.: Perspectives and potential roles for the newly discovered NSP4 in the immune system. Expert Review of Clinical Immunology 8 (6), S. 501 - 503 (2012)
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Perera, N. C.; Schilling, O.; Kittel, H.; Back, W.; Kremmer, E.; Jenne, D. E.: NSP4, an elastase-related protease in human neutrophils with arginine specificity. Proceedings of the National Academy of Sciences of the United States of America 109 (16), S. 6229 - 6234 (2012)
2011
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Croker, B. A.; Lewis, R. S.; Babon, J. J.; Mintern, J. D.; Jenne, D. E.; Metcalf, D.; Zhang, J. G.; Cengia, L. H.; O'Donnell, J. A.; Roberts, A. W.: Neutrophils require SHP1 to regulate IL-1β production and prevent inflammatory skin disease. Journal of Immunology 186 (2), S. 1131 - 1139 (2011)
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Kessenbrock, K.; Dau, T.; Jenne, D. E.: Tailor-made inflammation: How neutrophil serine proteases modulate the inflammatory response. Journal of Molecular Medicine 89 (1), S. 23 - 28 (2011)
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Motta, J. P.; Magne, L.; Descamps, D.; Rolland, C.; Squarzoni-Dale, C.; Rousset, P.; Martin, L.; Cenac, N.; Balloy, V.; Huerre, M. et al.; Frohlich, L. F.; Jenne, D. E.; Wartelle, J.; Belaaouaj, A.; Mas, E.; Vinel, J. P.; Alric, L.; Chignard, M.; Vergnolle, N.; Sallenave, J. M.: Modifying the protease, antiprotease pattern by elafin overexpression protects mice from colitis. Gastroenterology 140 (4), S. 1272 - 1282 (2011)
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Pröbstel, A.-K.; Dornmair, K.; Bittner, R.; Sperl, P.; Jenne, D. E.; Magalhaes, S.; Villalobos, A.; Breithaupt, C.; Weissert, R.; Jacob, U. et al.; Krumbholz, M.; Kuempfel, T.; Blaschek, A.; Stark, W.; Gaertner, J.; Pohl, D.; Rostasy, K.; Weber, F.; Forne, I.; Khademi, M.; Olsson, T.; Brilot, F.; Tantsis, E.; Dale, R. C.; Wekerle, H.; Hohlfeld, R.; Banwell, B.; Bar-Or, A.; Meinl, E.; Derfuss, T.: Antibodies to MOG are transient in childhood acute disseminated encephalomyelitis. Neurology 77 (6), S. 580 - 588 (2011)
2010
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Korkmaz, B.; Horwitz, M. S.; Jenne, D. E.; Gauthier, F.: Neutrophil Elastase, Proteinase 3, and Cathepsin G as Therapeutic Targets in Human Diseases. Pharmacological Reviews 62 (4), S. 726 - 759 (2010)
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Kuhl, A.; Korkmaz, B.; Utecht, B.; Kniepert, A.; Schonermarck, U.; Specks, U.; Jenne, D. E.: Mapping of Conformational Epitopes on Human Proteinase 3, the Autoantigen of Wegener's Granulomatosis. Journal of Immunology 185 (1), S. 387 - 399 (2010)
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Kurschus, F. C.; Jenne, D. E.: Delivery and therapeutic potential of human granzyme B. Immunological Reviews 235, S. 159 - 171 (2010)
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Silva, F.; Hummel, A. M.; Jenne, D. E.; Specks, U.: Discrimination and variable impact of ANCA binding to different surface epitopes on proteinase 3, the Wegener's autoantigen. Journal of Autoimmunity 35 (4), S. 299 - 308 (2010)
2009
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Kessenbrock, K.; Krumbholz, M.; Schönermarck, U.; Back, W.; Gross, W. L.; Werb, Z.; Gröne, H. J.; Brinkmann, V.; Jenne, D. E.: Netting neutrophils in autoimmune small-vessel vasculitis. Nature Medicine 15 (6), S. 623 - 625 (2009)
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Kurschus, F. C.; Pal, P. P.; Bäumler, P.; Jenne, D. E.; Wiltschi, B.; Budisa, N.: Gold Fluorescent Annexin A5 as a Novel Apoptosis Detection Tool. Cytometry Part A 75A (7), S. 626 - 633 (2009)
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