Max Planck Institute for Biological Intelligence

Publications of the research group "Tools for Bio-Imaging"

Journal Article (58)

2024

Journal Article

Nevelchuk, S.; Brawek, B.; Schwarz, N.; Valiente-Gabioud, A. A.; Wuttke, T. V.; Kovalchuk, Y.; Koch, H.; Höllig, A.; Steiner, F.; Figarella, K. et al.; Griesbeck, O.; Garaschuk, O.: Morphotype-specific calcium signaling in human microglia. Journal of Neuroinflammation 21 (1), 175 (2024)

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Journal Article

Ramazanov, B. R.; Parchure, A.; di Martino, R.; Kumar, A.; Chung, M.; Kim, Y.; Griesbeck, O.; Schwartz, M. A.; Luini, A.; von Blume, J.: Calcium flow at ER-TGN contact sites facilitates secretory cargo export. Molecular Biology of the Cell 35 (4), ar50 (2024)

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2023

Journal Article

Valiente-Gabioud, A. A.; Garteizgogeascoa Suñer, I.; Idziak, A.; Fabritius, A.; Basquin, J.; Angibaud, J.; Nägerl, U. V.; Singh, S. P.; Griesbeck, O.: Fluorescent sensors for imaging of interstitial calcium. Nature Communications 14, 6220 (2023)

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2022

Journal Article

Vicente, M.; Salgado-Almario, J.; Collins, M. M.; Martinez-Sielva, A.; Valiente-Gabioud, A. A.; Griesbeck, O.; Vincent, P.; Domingo, B.; Llopis, J.: Phenotyping calcium and contraction in a zebrafish model of phospholamban R9C mutation. Cardiovascular Research 118 (Suppl. 1), cvac066.125 (2022)

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Journal Article

Vicente, M.; Salgado-Almario, J.; Valiente-Gabioud, A. A.; Collins, M. M.; Vincent, P.; Domingo, B.; Llopis, J.: Early calcium and cardiac contraction defects in a model of phospholamban R9C mutation in zebrafish. Journal of Molecular and Cellular Cardiology (London) 173, pp. 127 - 140 (2022)

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2020

Journal Article

Erdogan, M.; Fabritius, A.; Basquin, J.; Griesbeck, O.: Targeted in situ protein diversification and intra-organelle validation in mammalian cells. Cell Chemical Biology 27 (5), pp. 610 - 621.e5 (2020)

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Journal Article

Xu, J.; Zeug, A.; Riederer, B.; Yeruva, S.; Griesbeck, O.; Daniel, H.; Tuo, B.; Ponimaskin, E.; Dong, H.; Seidler, U.: Calcium‐sensing receptor regulates intestinal dipeptide absorption via Ca2+ signaling and IKCa activation. Physiological Reports 8 (1), e14337 (2020)

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publisher-version

2019

Journal Article

Betolngar, D. B.; Mota, E.; Fabritius, A.; Nielsen, J.; Hougaard, C.; Christoffersen, C. T.; Yang, J.; Kehler, J.; Griesbeck, O.; Castro V, L. R. et al.; Vincent, P.: Phosphodiesterase 1 bridges glutamate inputs with NO- and dopamine-induced cyclic nucleotide signals in the striatum. Cerebral Cortex 29 (12), pp. 5022 - 5036 (2019)

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publisher-version

supplementary-material

Journal Article

Egbert, J. R.; Fahey, P. G.; Reimer, J.; Owen, C. M.; Evsikov, A. V.; Nikolaev, V. O.; Griesbeck, O.; Ray, R. S.; Tolias, A. S.; Jaffe, L. A.: Follicle-stimulating hormone and luteinizing hormone increase Ca2+ in the granulosa cells of mouse ovarian follicles. Biology of Reproduction 101 (2), pp. 433 - 444 (2019)

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publisher-version

Journal Article

Hofmann, U. A. T.; Fabritius, A.; Rebling, J.; Estrada, H.; Dean-Ben, X. L.; Griesbeck, O.; Razansky, D.: High-throughput platform for optoacoustic probing of genetically encoded calcium ion indicators. iScience 22, pp. 400 - 408 (2019)

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publisher-version

supplementary-material

Journal Article

Trigo-Mourino, P.; Thestrup, T.; Griesbeck, O.; Griesinger, C.; Becker, S.: Dynamic tuning of FRET in a green fluorescent protein biosensor. Science Advances 5 (8), eaaw4988 (2019)

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publisher-version

Journal Article

Witte, M. E.; Schumacher, A.-M.; Mahler, C. F.; Bewersdorf, J. P.; Lehmitz, J.; Scheiter, A.; Sanchez, P.; Williams, P. R.; Griesbeck, O.; Naumann, R. et al.; Misgeld, T.; Kerschensteiner, M.: Calcium influx through plasma-membrane nanoruptures drives Axon degeneration in a model of multiple sclerosis. Neuron 101 (4), pp. 615 - 624.e5 (2019)

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publisher-version

supplementary-material

2018

Journal Article

Fabritius, A.; Ng, D.; Kist, A. M.; Erdogan, M.; Portugues, R.; Griesbeck, O.: Imaging-based screening platform assists protein engineering. Cell Chemical Biology 25 (12), pp. 1554 - 1561.e8 (2018)

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Journal Article

Schnaitmann, C.; Haikala, V.; Abraham, E.; Oberhauser, V.; Thestrup, T.; Griesbeck, O.; Reiff, D. F.: Color processing in the early visual system of Drosophila. Cell 172 (1-2), pp. 318 - 330.e18 (2018)

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publisher-version

2015

Journal Article

Gopal, S.; Sogaard, P.; Multhaupt, H. A. B.; Pataki, C.; Okina, E.; Xian, X.; Pedersen, M. E.; Stevens, T.; Griesbeck, O.; Park, P. W. et al.; Pocock, R.; Couchman, J. R.: Transmembrane proteoglycans control stretch-activated channels to set cytosolic calcium levels. The Journal of Cell Biology 210 (7), pp. 1199 - 1211 (2015)

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Journal Article

Kovalchuk, Y.; Homma, R.; Liang, Y.; Maslyukov, A.; Hermes, M.; Thestrup, T.; Griesbeck, O.; Ninkovic, J.; Cohen, L. B.; Garaschuk, O.: In vivo odourant response properties of migrating adult-born neurons in the mouse olfactory bulb. Nature Communications 6, 6349 (2015)

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Journal Article

Litzlbauer, J.; Schifferer, M.; Ng, D.; Fabritius, A.; Thestrup, T.; Griesbeck, O.: Large scale bacterial colony screening of diversified FRET biosensors. PLoS One 10 (6), e0119860 (2015)

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Journal Article

Osswald, M.; Jung, E.; Sahm, F.; Solecki, G.; Venkataramani, V.; Blaes, J.; Weil, S.; Horstmann, H.; Wiestler, B.; Syed, M. et al.; Huang, L.; Ratliff, M.; Jazi, K. K.; Kurz, F. T.; Schmenger, T.; Lemke, D.; Goemmel, M.; Pauli, M.; Liao, Y.; Haering, P.; Pusch, S.; Herl, V.; Steinhaeuser, C.; Krunic, D.; Jarahian, M.; Miletic, H.; Berghoff, A. S.; Griesbeck, O.; Kalamakis, G.; Garaschuk, O.; Preusser, M.; Weiss, S.; Liu, H.; Heiland, S.; Platten, M.; Huber, P. E.; Kuner, T.; von Deimling, A.; Wick, W.; Winkler, F.: Brain tumour cells interconnect to a functional and resistant network. Nature 528 (7580), pp. 93 - 98 (2015)

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Journal Article

Siffrin, V.; Birkenstock, J.; Luchtman, D. W.; Gollan, R.; Baumgart, J.; Niesner, R. A.; Griesbeck, O.; Zipp, F.: FRET based ratiometric Ca2+ imaging to investigate immune-mediated neuronal and axonal damage processes in experimental autoimmune encephalomyelitis. Journal of Neuroscience Methods 249, pp. 8 - 15 (2015)

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2014

Journal Article

Breckwoldt, M.; Pfister, F. M. J.; Bradley, P. M.; Marinkovic, P.; Williams, P. R.; Brilll, M. S.; Plomer, B.; Schmalz, A.; St Clair, D. K.; Naumann, R. et al.; Griesbeck, O.; Schwarzlaender, M.; Godinho, L.; Bareyre, F. M.; Dick, T. P.; Kerschensteiner, M.; Misgeld, T.: Multiparametric optical analysis of mitochondrial redox signals during neuronal physiology and pathology in vivo. Nature Medicine 20 (5), pp. 555 - 560 (2014)

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Journal Article

Grimm, C.; Holdt, L. M.; Chen, C.-C.; Hassan, S.; Müller, C.; Jörs, S.; Cuny, H.; Kissing, S.; Schröder, B.; Butz, E. et al.; Northoff, B.; Castonguay, J.; Luber, C. A.; Moser, M.; Spahn, S.; Lüllmann-Rauch, R.; Fendel, C.; Klugbauer, N.; Griesbeck, O.; Haas, A.; Mann, M.; Bracher, F.; Teupser, D.; Saftig, P.; Biel, M.; Wahl-Schott, C.: High susceptibility to fatty liver disease in two-pore channel 2-deficient mice. Nature Communications 5, 4699 (2014)

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Journal Article

Rose, T.; Goltstein, P. M.; Portugues, R.; Griesbeck, O.: Putting a finishing touch on GECIs. Frontiers in Molecular Neuroscience 7, 88 (2014)

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Journal Article

Schoetz, U.; Deliolanis, N. C.; Ng, D.; Pauli, J.; Resch-Genger, U.; Kuehn, E.; Heuer, S.; Beisker, W.; Koester, R. W.; Zitzelsberger, H. et al.; Caldwell, R. B.: Usefulness of a Darwinian system in a biotechnological application: Evolution of optical window fluorescent protein variants under selective pressure. PLoS One 9 (9), e107069 (2014)

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Journal Article

Thestrup, T.; Litzlbauer, J.; Bartholomäus, I.; Mues, M.; Russo, L.; Dana, H.; Kovalchuk, Y.; Liang, Y.; Kalamakis, G.; Laukat, Y. et al.; Becker, S.; Witte, G.; Geiger, A.; Allen, T.; Rome, L. C.; Chen, T.-W.; Kim, D. S.; Garaschuk, O.; Griesinger, C.; Griesbeck, O.: Optimized ratiometric calcium sensors for functional in vivo imaging of neurons and T lymphocytes. Nature Methods 11 (2), pp. 175 - 182 (2014)

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Journal Article

Williams, P. R.; Marincu, B.-N.; Sorbara, C. D.; Mahler, C. F.; Schumacher, A.-M.; Griesbeck, O.; Kerschensteiner, M.; Misgeld, T.: A recoverable state of axon injury persists for hours after spinal cord contusion in vivo. Nature Communications 5, 5683 (2014)

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2013

Journal Article

Aramuni, G.; Griesbeck, O.: Chronic calcium imaging in neuronal development and disease. Experimental Neurology 242, pp. 50 - 56 (2013)

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Journal Article

Mues, M.; Bartholomäus, I.; Thestrup, T.; Griesbeck, O.; Wekerle, H.; Kawakami, N.; Krishnamoorthy, G.: Real-time in vivo analysis of T cell activation in the central nervous system using a genetically encoded calcium indicator. Nature Medicine 19 (6), pp. 778 - 783 (2013)

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2012

Journal Article

Direnberger, S.; Mues, M.; Micale, V.; Wotjak, C. T.; Dietzel, S.; Schubert, M.; Scharr, A.; Hassan, S.; Wahl-Schott, C.; Biel, M. et al.; Krishnamoorthy, G.; Griesbeck, O.: Biocompatibility of a genetically encoded calcium indicator in a transgenic mouse model. Nature Communications 3, 1031 (2012)

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Journal Article

Geiger, A.; Russo, L.; Gensch, T.; Thestrup, T.; Becker, S.; Hopfner, K. P.; Griesinger, C.; Witte, G.; Griesbeck, O.: Correlating calcium binding, Förster resonance energy transfer, and conformational change in the biosensor TN-XXL. Biophysical Journal 102 (10), pp. 2401 - 2410 (2012)

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Journal Article

Hu, Z.; Hom, S.; Kudze, T.; Tong, X.-J.; Choi, S.; Aramuni, G.; Zhang, W.; Kaplan, J. M.: Neurexin and neuroligin mediate retrograde synaptic inhibition in C. elegans. Science 337 (6097), pp. 980 - 984 (2012)

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Journal Article

Looger, L. L.; Griesbeck, O.: Genetically encoded neural activity indicators. Current Opinion in Neurobiology 22 (1), pp. 18 - 23 (2012)

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Journal Article

Schifferer, M.; Griesbeck, O.: A dynamic FRET reporter of gene expression improved by functional screening. Journal of the American Chemical Society 134 (37), pp. 15185 - 15188 (2012)

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Journal Article

Tay, L. H.; Dick, I. E.; Yang, W.; Mank, M.; Griesbeck, O.; Yue, D. T.: Nanodomain Ca2+ of Ca2+ channels detected by a tethered genetically encoded Ca2+ sensor. Nature Communications 3, 778 (2012)

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Journal Article

Wei, T.; Schubert, T.; Paquet-Durand, F.; Tanimoto, N.; Chang, L.; Koeppen, K.; Ott, T.; Griesbeck, O.; Seeliger, M. W.; Euler, T. et al.; Wissinger, B.: Light-driven calcium signals in mouse cone photoreceptors. The Journal of Neuroscience 32 (20), pp. 6981 - 6994 (2012)

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2011

Journal Article

Faumont, S.; Rondeau, G.; Thiele, T. R.; Lawton, K. J.; McCormick, K. E.; Sottile, M.; Griesbeck, O.; Heckscher, E. S.; Roberts, W. M.; Doe, C. Q. et al.; Lockery, S. R.: An image-free opto-mechanical system for creating virtual environments and imaging neuronal activity in freely moving Caenorhabditis elegans. PLoS One 6 (9), e24666 (2011)

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Journal Article

Ng, D. N.; Fromherz, P.: Genetic targeting of a voltage-sensitive dye by enzymatic activation of phosphonooxymethyl-ammonium derivative. ACS Chemical Biology 6 (5), pp. 444 - 451 (2011)

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Journal Article

Zhan, K.; Xie, H. X.; Gall, J.; Ma, M. L.; Griesbeck, O.; Salehi, A.; Rao, J. H.: Real-time imaging of Rab5 activity using a prequenched biosensor. ACS Chemical Biology 6 (7), pp. 692 - 699 (2011)

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2010

Journal Article

Friedrich, M. W.; Aramuni, G.; Mank, M.; Mackinnon, J. A. G.; Griesbeck, O.: Imaging CREB activation in living cells. The Journal of Biological Chemistry 285 (30), pp. 23285 - 23295 (2010)

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Journal Article

Nguyen, Q. T.; Schroeder, L. F.; Mank, M.; Muller, A.; Taylor, P.; Griesbeck, O.; Kleinfeld, D.: An in vivo biosensor for neurotransmitter release and in situ receptor activity. Nature Neuroscience 13 (1), pp. 127 - 132 (2010)

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Journal Article

Reiff, D. F.; Plett, J.; Mank, M.; Griesbeck, O.; Borst, A.: Visualizing retinotopic half-wave rectified input to the motion detection circuitry of Drosophila. Nature Neuroscience 13 (8), pp. 973 - 978 (2010)

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Journal Article

Siffrin, V.; Radbruch, H.; Glumm, R.; Niesner, R.; Paterka, M.; Herz, J.; Leuenberger, T.; Lehmann, S. M.; Luenstedt, S.; Rinnenthal, J. L. et al.; Laube, G.; Luche, H.; Lehnardt, S.; Fehling, H. J.; Griesbeck, O.; Zipp, F.: In vivo imaging of partially reversible Th17 cell-induced neuronal dysfunction in the course of encephalomyelitis. Immunity 33 (3), pp. 424 - 436 (2010)

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2009

Journal Article

Ducros, M.; Moreaux, L.; Bradley, J.; Tiret, P.; Griesbeck, O.; Charpak, S.: Spectral unmixing: Analysis of performance in the olfactory bulb in vivo. PLoS One 4 (2), e4418 (2009)

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Journal Article

Griessmeier, K.; Cuny, H.; Rötzer, K.; Griesbeck, O.; Harz, H.; Biel, M.; Wahl-Schott, C.: Calmodulin is a functional regulator of Cav1.4 L-type Ca2+ channels. The Journal of Biological Chemistry 284 (43), pp. 29809 - 29816 (2009)

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Journal Article

Hou, B. H.; Takanaga, H.; Griesbeck, O.; Frommer, W. B.: Osmotic induction of calcium accumulation in human embryonic kidney cells detected with a high sensitivity FRET calcium sensor. Cell Calcium 46 (2), pp. 130 - 135 (2009)

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Journal Article

Schifferer, M.; Griesbeck, O.: Application of aptamers and autofluorescent proteins for RNA visualization. Integrative Biology 1 (8-9), pp. 499 - 505 (2009)

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Journal Article

Zong, X. G.; Schieder, M.; Cuny, H.; Fenske, S.; Gruner, C.; Rötzer, K.; Griesbeck, O.; Harz, H.; Biel, M.; Wahl-Schott, C.: The two-pore channel TPCN2 mediates NAADP-dependent Ca2+-release from lysosomal stores. Pflügers Archiv: European Journal of Physiology 458 (5), pp. 891 - 899 (2009)

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2008

Journal Article

Hendel, T.; Mank, M.; Schnell, B.; Griesbeck, O.; Borst, A.; Reiff, D. F.: Fluorescence changes of genetic calcium indicators and OGB-1 correlated with neural activity and calcium in vivo and in vitro. The Journal of Neuroscience 28 (29), pp. 7399 - 7411 (2008)

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Journal Article

Mank, M.; Ferrao Santos, A.; Direnberger, S.; Mrsic-Flogel, T. D.; Hofer, S. B.; Stein, V.; Hendel, T.; Reiff, D. F.; Levelt, C.; Borst, A. et al.; Bonhoeffer, T.; Hübener, M.; Griesbeck, O.: A genetically encoded calcium indicator for chronic in vivo two-photon imaging. Nature Methods 5 (9), pp. 805 - 811 (2008)

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Journal Article

Mank, M.; Griesbeck, O.: Genetically encoded calcium indicators. Chemical Reviews 108 (5), pp. 1550 - 1564 (2008)

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2007

Journal Article

Garaschuk, O.; Griesbeck, O.; Konnerth, A.: Troponin C-based biosensors: A new family of genetically encoded indicators for in vivo calcium imaging in the nervous system. Cell Calcium 42 (4-5), pp. 351 - 361 (2007)

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