Publications of Tobias Bonhoeffer

2024

Journal Article

Bauer, J.; Lewin, U.; Herbert, E.; Gjorgjieva, J.; Schoonover, C.; Fink, A.; Rose, T.; Bonhoeffer, T.; Hübener, M.: Sensory experience steers representational drift in mouse visual cortex. Nature Communications 15, 9153 (2024)

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Journal Article

Fernholz, M. H. P.; Guggiana Nilo, D.; Bonhoeffer, T.; Kist, A. M.: DeepD3, an open framework for automated quantification of dendritic spines. PLoS Computational Biology 20 (2), e1011774 (2024)

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Journal Article

Hille, M.; Kühn, S.; Kempermann, G.; Bonhoeffer, T.; Lindenberger, U.: From animal models to human individuality: Integrative approaches to the study of brain plasticity. Neuron 112 (21), pp. 3522 - 3541 (2024)

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2023

Journal Article

Weiler, S.; Guggiana Nilo, D.; Bonhoeffer, T.; Hübener, M.; Rose, T.; Scheuss, V.: Functional and structural features of L2/3 pyramidal cells continuously covary with pial depth in mouse visual cortex. Cerebral Cortex 33 (7), pp. 3715 - 3733 (2023)

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2022

Journal Article

Obenhaus, H. A.; Zong, W.; Jacobsen, R. I.; Rose, T.; Donato, F.; Chen, L.; Cheng, H.; Bonhoeffer, T.; Moser, M.-B.; Moser, E. I.: Functional network topography of the medial entorhinal cortex. Proceedings of the National Academy of Sciences of the United States of America 119 (7), e2121655119 (2022)

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Journal Article

Weiler, S.; Guggiana Nilo, D.; Bonhoeffer, T.; Hübener, M.; Rose, T.; Scheuss, V.: Orientation and direction tuning align with dendritic morphology and spatial connectivity in mouse visual cortex. Current Biology 32 (8), pp. 1743 - 1753.e7 (2022)

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2021

Journal Article

Bauer, J.; Weiler, S.; Fernholz, M. H. P.; Laubender, D.; Scheuss, V.; Hübener, M.; Bonhoeffer, T.; Rose, T.: Limited functional convergence of eye-specific inputs in the retinogeniculate pathway of the mouse. Neuron 109 (15), pp. 2457 - 2468 (2021)

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Journal Article

Glas, A.; Hübener, M.; Bonhoeffer, T.; Goltstein, P. M.: Spaced training enhances memory and prefrontal ensemble stability in mice. Current Biology 31 (18), pp. 4052 - 4061.e6 (2021)

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supplementary-material

Journal Article

Goltstein, P. M.; Reinert, S.; Bonhoeffer, T.; Hübener, M.: Mouse visual cortex areas represent perceptual and semantic features of learned visual categories. Nature Neuroscience 24 (10), pp. 1441 - 1451 (2021)

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Journal Article

Reinert, S.; Hübener, M.; Bonhoeffer, T.; Goltstein, P. M.: Mouse prefrontal cortex represents learned rules for categorization. Nature 593 (7859), pp. 411 - 417 (2021)

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2020

Journal Article

La Chioma, A.; Bonhoeffer, T.; Hübener, M.: Disparity sensitivity and binocular integration in mouse visual cortex areas. The Journal of Neuroscience 40 (46), pp. 8883 - 8899 (2020)

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2019

Journal Article

Glas, A.; Hübener, M.; Bonhoeffer, T.; Goltstein, P. M.: Benchmarking miniaturized microscopy against two-photon calcium imaging using single-cell orientation tuning in mouse visual cortex. PLoS One 14 (4), e0214954 (2019)

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Journal Article

La Chioma, A.; Bonhoeffer, T.; Hübener, M.: Area-specific mapping of binocular disparity across mouse visual cortex. Current Biology 29 (17), pp. 2954 - 2960.e5 (2019)

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2018

Journal Article

Goltstein, P. M.; Reinert, S.; Glas, A.; Bonhoeffer, T.; Hübener, M.: Food and water restriction lead to differential learning behaviors in a head-fixed two-choice visual discrimination task for mice. PLoS One 13 (9), e0204066 (2018)

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ZIP

Journal Article

Rose, T.; Bonhoeffer, T.: Experience-dependent plasticity in the lateral geniculate nucleus. Current Opinion in Neurobiology 53, pp. 22 - 28 (2018)

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Journal Article

Weiler, S.; Bauer, J.; Hübener, M.; Bonhoeffer, T.; Rose, T.; Scheuss, V.: High-yield in vitro recordings from neurons functionally characterized in vivo. Nature Protocols 13 (6), pp. 1275 - 1293 (2018)

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2017

Journal Article

Clopath, C.; Bonhoeffer, T.; Hübener, M.; Rose, T.: Variance and invariance of neuronal long-term representations. Philosophical Transactions of the Royal Society of London, Series B: Biological Sciences 372 (1715), 20160161 (2017)

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Journal Article

Jaepel, J.; Hübener, M.; Bonhoeffer, T.; Rose, T.: Lateral geniculate neurons projecting to primary visual cortex show ocular dominance plasticity in adult mice. Nature Neuroscience 20 (12), pp. 1708 - 1714 (2017)

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Journal Article

Keck, T.; Hübener, M.; Bonhoeffer, T.: Interactions between synaptic homeostatic mechanisms: An attempt to reconcile BCM theory, synaptic scaling, and changing excitation/inhibition balance. Current Opinion in Neurobiology 43, pp. 87 - 93 (2017)

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Journal Article

Lissek, T.; Adams, M.; Adelman, J.; Ahissar, E.; Akaaboune, M.; Akil, H.; al'Absi, M.; Arain, F.; Arango-Lasprilla, J. C.; Atasoy, D. et al.; Avila, J.; Badawi, A.; Bading, H.; Baig, A. M.; Baleriola, J.; Belmonte, C.; Bertocci, I.; Betz, H.; Blakemore, C.; Blanke, O.; Boehm-Sturm, P.; Bonhoeffer, T.; Bonifazi, P.; Brose, N.; Campolongo, P.; Celikel, T.; Chang, C. C.; Chang, T. Y.; Citri, A.; Cline, H. T.; Cortes, J. M.; Cullen, K.; Dean, K.; Delgado-Garcia, J. M.; Desroches, M.; Disterhoft, J. M.; Dowling, J. E.; Draguhn, A.; El-Kamisky, S. F.; El Manira, A.; Enam, S. A.; Encinas, J. M.; Erramuzpe, A.; Esteban, J. A.; Farinas, I.; Fischer, E.; Fukunaga, I.; Gabilondo, I.; Ganten, D.; Gidon, A.; Gomez-Esteban, J. C.; Greengard, P.; Grinevich, V. ..; Gruart, A.; Gueillemin, R.; Hariri, A. R.; Hassan, B.; Häusser, M.; Hayashi, Y.; Hussain, N. K.; Jabbar, A. A.; Jaber, M.; Jahn, R.; Janahi, E. M.; Kabbaj, M.; Kettenmann, H.; Kindt, M.; Knafo, S.; Köhr, G.; Komai, S.; Krugers, H.; Kuhn, B.; Ghazal, N. L.; Larkum, M. E.; London, M.; Lutz, B.; Matute, C.; Martinez-Millan, L.; Maroun, M.; Mc Gaugh, J.; Moustafa, A. A.; Nasim, A.; Nave, K. A.; Neher, E.; Nikolich, K.; Outeiro, T.; Palmer, L. M.; Penagarikano, O.; Perez-Otano, I.; Pfaff, D. W.; Poucet, B.; Rahman, A. U.; Ramos-Cabrer, P.; Rashidy-Pour, A.; Roberts, R. J.; Rodrigues, S.; Sanes, J. R.; Schaefer, A. T.; Segal, M.; Segev, I.; Shafqat, S.; Siddiqui, N. A.; Soreq, H.; Soriano-Garcia, E.; Spanagel, R.; Sprengel, R.; Stuart, G.; Südhof, T. C.; Tønnesen, J.; Trevino, M.; Uthman, B. M.; Venter, J. C.; Verkhratsky, A.; Weiss, C.; Wiesel, T. N.; Yaksi, E.; Yizhar, O.; Young, L. J.; Young, P.; Zawia, N. H.; Zugaza, J. L.; Hasan, M. T.: Building bridges through science. Neuron 96 (4), pp. 730 - 735 (2017)

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2016

Journal Article

Falkner, S.; Grade, S.; Dimou, L.; Conzelmann, K.-K.; Bonhoeffer, T.; Goetz, M.; Hübener, M.: Transplanted embryonic neurons integrate into adult neocortical circuits. Nature 539 (7628), pp. 248 - 253 (2016)

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Journal Article

Gökce, O.; Bonhoeffer, T.; Scheuss, V.: Clusters of synaptic inputs on dendrites of layer 5 pyramidal cells in mouse visual cortex. eLife 5, e09222 (2016)

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supplementary-material

Journal Article

Liebscher, S.; Keller, G. B.; Goltstein, P. M.; Bonhoeffer, T.; Hübener, M.: Selective persistence of sensorimotor mismatch signals in visual cortex of behaving Alzheimer's disease mice. Current Biology 26 (7), pp. 956 - 964 (2016)

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Journal Article

Poo, M.-m.; Pignatelli, M.; Ryan, T. J.; Tonegawa, S.; Bonhoeffer, T.; Martin, K. C.; Rudenko, A.; Tsai, L.-H.; Tsien, R. W.; Fishell, G. et al.; Mullins, C.; Goncalves, J. T.; Shtrahman, M.; Johnston, S. T.; Gage, F. H.; Dan, Y.; Long, J.; Buzsaki, G.; Stevens, C.: What is memory? The present state of the engram. BMC Biology 14, 40 (2016)

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Journal Article

Rose, T.; Jaepel, J.; Hübener, M.; Bonhoeffer, T.: Cell-specific restoration of stimulus preference after monocular deprivation in the visual cortex. Science 352 (6291), pp. 1319 - 1322 (2016)

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Journal Article

Schinder, A. F.; Bonhoeffer, T.; Sperling, R.; Dudai, Y.; Marin, O.; Morris, R.; Mrsic-Flogel, T.: Organizing brain science on an international scale. Neuron 92 (3), pp. 567 - 569 (2016)

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2015

Journal Article

Müllner, F. E.; Wierenga, C. J.; Bonhoeffer, T.: Precision of inhibition: Dendritic inhibition by individual GABAergic synapses on hippocampal pyramidal cells is confined in space and time. Neuron 87 (3), pp. 576 - 589 (2015)

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2014

Journal Article

Hübener, M.; Bonhoeffer, T.: Neuronal plasticity: Beyond the critical period. Cell 159 (4), pp. 727 - 737 (2014)

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Journal Article

Leinweber, M.; Zmarz, P.; Buchmann, P.; Argast, P.; Hübener, M.; Bonhoeffer, T.; Keller, G. B.: Two-photon calcium imaging in mice navigating a virtual reality environment. Journal of Visualized Experiments 84, e50885 (2014)

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Journal Article

Liebscher, S.; Page, R. M.; Käfer, K.; Winkler, E.; Quinn, K.; Goldbach, E.; Brigham, E. F.; Quincy, D.; Basi, G. S.; Schenk, D. B. et al.; Steiner, H.; Bonhoeffer, T.; Haass, C.; Meyer-Luehmann, M.; Hübener, M.: Chronic γ-secretase inhibition reduces amyloid plaque-associated instability of pre- and postsynaptic structures. Molecular Psychiatry 19 (8), pp. 937 - 946 (2014)

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Journal Article

Meyer, D.; Bonhoeffer, T.; Scheuss, V.: Balance and stability of synaptic structures during synaptic plasticity. Neuron 82 (2), pp. 430 - 443 (2014)

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Journal Article

Moser, E. I.; Roudi, Y.; Witter, M. P.; Kentros, C.; Bonhoeffer, T.; Moser, M.-B.: Grid cells and cortical representation. Nature Reviews Neuroscience 15 (7), pp. 466 - 481 (2014)

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Journal Article

Scheuss, V.; Bonhoeffer, T.: Function of dendritic spines on hippocampal inhibitory neurons. Cerebral Cortex 24 (12), pp. 3142 - 3153 (2014)

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2013

Journal Article

Keck, T.; Keller, G. B.; Jacobsen, R. I.; Eysel, U. T.; Bonhoeffer, T.; Hübener, M.: Synaptic scaling and homeostatic plasticity in the mouse visual cortex in vivo. Neuron 80 (2), pp. 327 - 334 (2013)

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Journal Article

Schuemann, A.; Klawiter, A.; Bonhoeffer, T.; Wierenga, C. J.: Structural plasticity of GABAergic axons is regulated by network activity and GABA(A) receptor activation. Frontiers in Neural Circuits 7, 113 (2013)

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Journal Article

Tomita, K.; Sperling, M.; Cambridge, S. B.; Bonhoeffer, T.; Hübener, M.: A molecular correlate of ocular dominance columns in the developing mammalian visual cortex. Cerebral Cortex 23 (11), pp. 2531 - 2541 (2013)

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2012

Journal Article

Keller, G. B.; Bonhoeffer, T.; Hübener, M.: Sensorimotor mismatch signals in primary visual cortex of the behaving mouse. Neuron 74 (5), pp. 809 - 815 (2012)

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Journal Article

Mrsic-Flogel, T. D.; Bonhoeffer, T.: Sibling neurons bond to share sensations. Nature 486 (7401), pp. 41 - 42 (2012)

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2011

Journal Article

Keck, T.; Scheuss, V.; Jacobsen, R. I.; Wierenga, C. J.; Eysel, U. T.; Bonhoeffer, T.; Hübener, M.: Loss of sensory input causes rapid structural changes of inhibitory neurons in adult mouse visual cortex. Neuron 71 (5), pp. 869 - 882 (2011)

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Journal Article

Kleindienst, T.; Winnubst, J.; Roth-Alpermann, C.; Bonhoeffer, T.; Lohmann, C.: Activity-dependent clustering of functional synaptic inputs on developing hippocampal dendrites. Neuron 72 (6), pp. 1012 - 1024 (2011)

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Journal Article

Kreile, A. K.; Bonhoeffer, T.; Hübener, M.: Altered visual experience induces instructive changes of orientation preference in mouse visual cortex. The Journal of Neuroscience 31 (39), pp. 13911 - 13920 (2011)

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2010

Journal Article

Hofer, S. B.; Bonhoeffer, T.: Dendritic spines: The stuff that memories are made of? Current Biology 20 (4), pp. R157 - R159 (2010)

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Journal Article

Hübener, M.; Bonhoeffer, T.: Searching for Engrams. Neuron 67 (3), pp. 363 - 371 (2010)

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Journal Article

Nägerl, U. V.; Bonhoeffer, T.: Imaging living synapses at the nanoscale by STED microscopy. The Journal of Neuroscience 30 (28), pp. 9341 - 9346 (2010)

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Journal Article

Wierenga, C. J.; Müllner, F. E.; Rinke, I.; Keck, T.; Stein, V.; Bonhoeffer, T.: Molecular and electrophysiological characterization of GFP expressing CA1 interneurons in GAD65-GFP mice. PLoS One 5 (12), e15915 (2010)

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2009

Journal Article

Bonhoeffer, T.; Tessier-Lavigne, M.: The next decade of Current Opinion in Neurobiology. Current Opinion in Neurobiology 19 (6), p. 569 - 569 (2009)

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Journal Article

Cambridge, S. B.; Geissler, D.; Calegari, F.; Anastassiadis, K.; Hasan, M. T.; Stewart, A. F.; Huttner, W. B.; Hagen, V.; Bonhoeffer, T.: Doxycycline-dependent photoactivated gene expression in eukaryotic systems. Nature Methods 6 (7), pp. 527 - 531 (2009)

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Journal Article

Hofer, S. B.; Mrsic-Flogel, T. D.; Bonhoeffer, T.; Hübener, M.: Experience leaves a lasting structural trace in cortical circuits. Nature 457 (7227), pp. 313 - 317 (2009)

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Journal Article

Holtmaat, A.; Bonhoeffer, T.; Chow, D. K.; Chuckowree, J.; De Paola, V.; Hofer, S. B.; Hübener, M.; Keck, T.; Knott, G.; Lee, W. C. A. et al.; Mostany, R.; Mrsic-Flogel, T. D.; Nedivi, E.; Portera-Cailliau, C.; Svoboda, K.; Trachtenberg, J. T.; Wilbrecht, L.: Long-term, high-resolution imaging in the mouse neocortex through a chronic cranial window. Nature Protocols 4 (8), pp. 1128 - 1144 (2009)

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