Publications of Klaus Dornmair

Journal Article (33)

2012
Journal Article
Bruder, J.; Siewert, K.; Obermeier, B.; Malotka, J.; Scheinert, P.; Kellermann, J.; Ueda, T.; Hohlfeld, R.; Dornmair, K.: Target specificity of an autoreactive pathogenic human gamma delta-T cell receptor in myositis. The Journal of Biological Chemistry 287 (25), pp. 20986 - 20995 (2012)
Journal Article
Held, K.; Eiglmeier, I.; Himmelein, S.; Sinicina, I.; Brandt, T.; Theil, D.; Dornmair, K.; Derfuss, T.: Clonal expansions of CD8(+) T cells in latently HSV-1-infected human trigeminal ganglia. Journal of NeuroVirology 18 (1), pp. 62 - 68 (2012)
Journal Article
Kim, S.-M.; Bhonsle, L.; Besgen, P.; Nickel, J.; Backes, A.; Held, K.; Vollmer, S.; Dornmair, K.; Prinz, J. C.: Analysis of the paired TCR alpha- and beta-chains of single human T cells. PLoS One 7 (5), e37338 (2012)
Journal Article
Ng, J. K. M.; Malotka, J.; Kawakami, N.; Derfuss, T.; Khademi, M.; Olsson, T.; Linington, C.; Odaka, M.; Tackenberg, B.; Pruess, H. et al.; Schwab, J. M.; Harms, L.; Harms, H.; Sommer, C.; Rasband, M. N.; Eshed-Eisenbach, Y.; Peles, E.; Hohlfeld, R.; Yuki, N.; Dornmair, K.; Meinl, E.: Neurofascin as a target for autoantibodies in peripheral neuropathies. Neurology 79 (23), pp. 2241 - 2248 (2012)
Journal Article
Siewert, K.; Malotka, J.; Kawakami, N.; Wekerle, H.; Hohlfeld, R.; Dornmair, K.: Unbiased identification of target antigens of CD8(+) T cells with combinatorial libraries coding for short peptides. Nature Medicine 18 (5), pp. 824 - 828 (2012)
2011
Journal Article
Held, K.; Junker, A.; Dornmair, K.; Meinl, E.; Sinicina, I.; Brandt, T.; Theil, D.; Derfuss, T.: Expression of herpes simplex virus 1-encoded microRNAs in human trigeminal ganglia and their relation to local T-cell infiltrates. Journal of Virology 85 (19), pp. 9680 - 9685 (2011)
Journal Article
Ivanidze, J.; Hoffmann, R.; Lochmueller, H.; Engel, A. G.; Hohlfeld, R.; Dornmair, K.: Inclusion body myositis laser microdissection reveals differential up-regulation of IFN-gamma signaling cascade in attacked versus nonattacked myofibers. American Journal of Pathology 179 (3), pp. 1347 - 1359 (2011)
Journal Article
Obermeier, B.; Lovato, L.; Bruck, W.; Forne, I.; Imhof, A.; Mentele, R.; Lottspeich, F.; Turk, K. W.; Willis, S. N.; Wekerle, H. et al.; Hohlfeld, R.; Hafler, D. A.; O'Connor, K. C.; Dornmair, K.: Related B cell clones that populate the CSF and CNS of patients with multiple sclerosis produce CSF immunoglobulin. Journal of Neuroimmunology 233 (1-2), pp. 245 - 248 (2011)
Journal Article
Pröbstel, A.-K.; Dornmair, K.; Bittner, R.; Sperl, P.; Jenne, D. E.; Magalhaes, S.; Villalobos, A.; Breithaupt, C.; Weissert, R.; Jacob, U. et al.; Krumbholz, M.; Kuempfel, T.; Blaschek, A.; Stark, W.; Gaertner, J.; Pohl, D.; Rostasy, K.; Weber, F.; Forne, I.; Khademi, M.; Olsson, T.; Brilot, F.; Tantsis, E.; Dale, R. C.; Wekerle, H.; Hohlfeld, R.; Banwell, B.; Bar-Or, A.; Meinl, E.; Derfuss, T.: Antibodies to MOG are transient in childhood acute disseminated encephalomyelitis. Neurology 77 (6), pp. 580 - 588 (2011)
Journal Article
Schuster, F. R.; Hubner, B.; Fuehrer, M.; Eckermann, O.; Gombert, M.; Dornmair, K.; Binder, V.; Reuther, S.; Krell, P.; Keller, T. et al.; Borkhardt, A.: Highly skewed T-cell receptor V-beta chain repertoire in the bone marrow is associated with response to immunosuppressive drug therapy in children with very severe aplastic anemia. Blood Cancer Journal 1, e8 (2011)
2010
Journal Article
Cordiglieri, C.; Odoardi, F.; Zhang, B.; Nebel, M.; Kawakami, N.; Klinkert, W. E. F.; Lodygin, D.; Luhder, F.; Breunig, E.; Schild, D. et al.; Ulaganathan, V. K.; Dornmair, K.; Dammermann, W.; Potter, B. V. L.; Guse, A. H.; Flügel, A.: Nicotinic acid adenine dinucleotide phosphate-mediated calcium signalling in effector T cells regulates autoimmunity of the central nervous system. Brain 133, pp. 1930 - 1943 (2010)
2009
Journal Article
Dammermann, W.; Zhang, B.; Nebel, M.; Cordiglieri, C.; Odoardi, F.; Kirchberger, T.; Kawakami, N.; Dowden, J.; Schmid, F.; Dornmair, K. et al.; Hohenegger, M.; Flügel, A.; Guse, A. H.; Potter, B. V. L.: NAADP-mediated Ca2+ signaling via type 1 ryanodine receptor in T cells revealed by a synthetic NAADP antagonist. Proceedings of the National Academy of Sciences of the United States of America 106 (26), pp. 10678 - 10683 (2009)
Journal Article
Dornmair, K.; Meinl, E.; Hohlfeld, R.: Novel approaches for identifying target antigens of autoreactive human B and T cells. Seminars in Immunopathology 31 (4), pp. 467 - 477 (2009)
Journal Article
Krishnamoorthy, G.; Saxena, A.; Mars, L. T.; Domingues, H. S.; Ben-Nun, A.; Lassmann, H.; Dornmair, K.; Mentele, R.; Kurschus, F. C.; Liblau, R. S. et al.; Wekerle, H.: Myelin-specific T cells also recognize neuronal autoantigen in a transgenic mouse model of multiple sclerosis. Nature Medicine 15 (6), pp. 626 - 632 (2009)
Journal Article
Lahl, K.; Mayer, C. T.; Bopp, T.; Huehn, J.; Loddenkemper, C.; Eberl, G.; Wirnsberger, G.; Dornmair, K.; Geffers, R.; Schmitt, E. et al.; Buer, J.; Sparwasser, T.: Nonfunctional Regulatory T Cells and Defective Control of Th2 Cytokine Production in Natural Scurfy Mutant Mice. Journal of Immunology 183 (9), pp. 5662 - 5672 (2009)
Journal Article
Pellkofer, H. L.; Voltz, R.; Goebels, N.; Hohlfeld, R.; Dornmair, K.: Cross-reactive T-Cell Receptors in Tumor and Paraneoplastic Target Tissue. Archives of Neurology 66 (5), pp. 655 - 658 (2009)
Journal Article
Schwab, N.; Bien, C.G.; Waschbisch, A.; Becker, A.; Vince, G.H.; Dornmair, K.; Wiendl, H.: CD8+ T-cell clones dominate brain infiltrates in Rasmussen encephalitis and persist in the periphery. Brain 132 (5), pp. 1236 - 1246 (2009)
2008
Journal Article
Deininger, K.; Eder, M.; Kramer, E. R.; Zieglgänsberger, W.; Dodt, H. U.; Dornmair, K.; Colicelli, J.; Klein, R.: The Rab5 guanylate exchange factor Rin1 regulates endocytosis of the EphA4 receptor in mature excitatory neurons. Proceedings of the National Academy of Sciences of the United States of America 105 (34), pp. 12539 - 12544 (2008)
Journal Article
Hohlfeld, R.; Meinl, E.; Dornmair, K.: B- and T-cell responses in multiple sclerosis: Novel approaches offer new insights. Journal of Neurological Sciences 274 (1-2), pp. 5 - 8 (2008)
Journal Article
Obermeier, B.; Malotka, J.; Dornmair, K.; Mentele, R.: Analysis of patient-specific immunoglobulin proteomes and transcriptomes by PCR cloning and mass spectometry. (2008)
Journal Article
Obermeier, B.; Malotka, J.; Kellermann, J.; Kümpfel, T.; Wekerle, H.; Lottspeich, F.; Mentele, R.; Hohlfeld, R.; Dornmair, K.: Matching of oligoclonal immunoglobulin transcriptomes and proteomes of cerebrospinal fluid in multiple sclerosis. Nature Medicine 14 (6), pp. 688 - 693 (2008)
2007
Journal Article
Derfuss, T.; Segerer, S.; Herberger, S.; Sinicina, I.; Hufner, K.; Ebelt, K.; Knaus, H. G.; Steiner, I.; Meinl, E.; Dornmair, K. et al.; Arbusow, V.; Strupp, M.; Brandt, T.; Theil, D.: Presence of HSV-1 immediate early genes and clonally expanded T-cells with a memory effector phenotype in human trigeminal ganglia. Brain Pathology 17 (4), pp. 389 - 398 (2007)
Journal Article
Grundtner, R.; Dornmair, K.; Dahm, R.; Flügel, A.; Kawakami, N.; Zeitelhofer, M.; Schoderboeck, L.; Nosov, M.; Selzer, E.; Willheim, M. et al.; Kiebler, M.; Wekerle, H.; Lassmann, H.; Bradl, M.: Transition from enhanced T cell infiltration to inflammation in the myelin-degenerative central nervous system. Neurobiology of Disease 28 (3), pp. 261 - 275 (2007)
Journal Article
Hohlfeld, R.; Dornmair, K.: Revisiting the immunopathogenesis of the inflammatory myopathies. Neurology 69 (21), pp. 1966 - 1967 (2007)
Journal Article
Junker, A.; Ivanidze, J.; Malotka, J.; Eiglmeier, I.; Lassmann, H.; Wekerle, H.; Meinl, E.; Hohlfeld, R.; Dornmair, K.: Multiple sclerosis: T-cell receptor expression in distinct brain regions. Brain 130, pp. 2789 - 2799 (2007)
Journal Article
Leder, C.; Schwab, N.; Ip, C. W.; Kroner, A.; Nave, K. A.; Dornmair, K.; Martini, R.; Wiendl, H.: Clonal expansions of pathogenic CD8+ effector cells in the CNS of myelin mutant mice. Molecular and Cellular Neuroscience 36 (3), pp. 416 - 424 (2007)
2006
Journal Article
Seitz, S.; Schneider, C. K.; Malotka, J.; Nong, X.; Engel, A. G.; Wekerle, H.; Hohlfeld, R.; Dornmair, K.: Reconstitution of paired T cell receptor alpha- and beta-chains from microdissected single cells of human inflammatory tissues. Proceedings of the National Academy of Sciences of the United States of America 103 (32), pp. 12057 - 12062 (2006)
2004
Journal Article
Dornmair, K.; Schneider, C. K.; Malotka, J.; Dechant, G.; Wiendl, H.; Hohlfeld, R.: Antigen recognition properties of a V gamma LW delta 2-T-cell receptor from a rare variant of polymyositis. Journal of Neuroimmunology 152 (1-2), pp. 168 - 175 (2004)
Journal Article
Kurschus, F. C.; Kleinschmidt, M.; Fellows, E.; Dornmair, K.; Rudolph, R.; Lilie, H.; Jenne, D. E.: Killing of target cells by redirected granzyme B in the absence of perforin. FEBS Letters 562 (1-3), pp. 87 - 92 (2004)
Journal Article
Skulina, C.; Schmidt, S.; Dornmair, K.; Babbe, H.; Roers, A.; Rajewsky, K.; Wekerle, H.; Hohlfeld, R.; Goebels, N.: Multiple sclerosis: Brain-infiltrating CD8(+) T cells persist as clonal expansions in the cerebrospinal fluid and blood. Proceedings of the National Academy of Sciences of the United States of America 101 (8), pp. 2428 - 2433 (2004)
2003
Journal Article
Dornmair, K.; Goebels, N.; Weltzien, H. U.; Wekerle, H.; Hohlfeld, R.: T-cell-mediated autoimmunity - Novel techniques to characterize autoreactive T-cell receptors. American Journal of Pathology 163 (4), pp. 1215 - 1226 (2003)
Journal Article
Hofbauer, M.; Wiesener, S.; Babbe, H.; Roers, A.; Wekerle, H.; Dornmair, K.; Goebels, N.: Clonal tracking of autoaggressive T cells in polymyositis by combining laser microdissection, single-cell PCR, and CDR3-spectratype analysis. Proceedings of the National Academy of Sciences U S A 100 (7), pp. 4090 - 4095 (2003)
2002
Journal Article
Wiendl, H.; Malotka, J.; Holzwarth, B.; Weltzien, H. U.; Wekerle, H.; Hohlfeld, R.; Dornmair, K.: An autoreactive gamma delta TCR derived from a polymyositis lesion. Journal of Immunology 169 (1), pp. 515 - 521 (2002)

Book Chapter (1)

2008
Book Chapter
Bradl, M.; Dornmair, K.; Hohlfeld, R.: New tools for investigating the immunopathogenesis of MS: Principles and applications. In: Multiple Sclerosis: A Comprehensive Text, pp. 284 - 299 (Eds. Raine, C. S.; McFarland, H. F.; Hohlfeld, R.). Saunders, Elsevier, Edinburgh (2008)

Thesis - Habilitation (1)

2010
Thesis - Habilitation
Dornmair, K.: Funktionelle Charakterisierung von autoaggressiven Lymphozyten aus Biopsieproben. Habilitation, Ludwig-Maximilians-Universität, München (2010)
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