Designer Proteins for Brain Research

Research report (imported) 2018 - Max-Planck-Institut für Neurobiologie

Griesbeck, Oliver
Forschungsgruppe Tools for Bio-Imaging
Directed evolution of proteins in vitro harbors great potential to generate tailor-made tools for applications in neuroscience. Our group has built an imaging-based screening platform that allows high throughput validation of hundred thousands of protein variants expressed in bacteria. We have used the platform to optimize a fluorescent protein that is particularly useful for labeling structures that are located deep within the brain.

For the full text, see the German version.

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