Publications of Rüdiger Klein

Journal Article (186)

1996
Journal Article
Brambilla, R.; Brückner, K.; Orioli, D.; Bergemann, A. D.; Flanagan, J. G.; Klein, R.: Similarities and differences in the way transmembrane-type ligands interact with the Elk subclass of Eph receptors. Molecular and Cellular Neuroscience 8 (2-3), pp. 199 - 209 (1996)
Journal Article
Henkemeyer, M.; Orioli, D.; Henderson, J. T.; Saxton, T. M.; Roder, J.; Pawson, T.; Klein, R.: Nuk controls pathfinding of commissural axons in the mammalian central nervous system. Cell 86 (1), pp. 35 - 46 (1996)
Journal Article
Maina, F.; Casagranda, F.; Audero, E.; Simeone, A.; Comoglio, P. M.; Klein, R.; Ponzetto, C.: Uncoupling of Grb2 from the Met receptor in vivo reveals complex roles in muscle development. Cell 87 (3), pp. 531 - 542 (1996)
Journal Article
Minichiello, L.; Klein, R.: TrkB and TrkC neurotrophin receptors cooperate in promoting survival of hippocampal and cerebellar granule neurons. Genes and Development 10 (22), pp. 2849 - 2858 (1996)
Journal Article
Orioli, D.; Henkemeyer, M.; Lempe, G.; Klein, R.; Pawson, T.: Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation. The EMBO Journal 15 (22), pp. 6035 - 6049 (1996)
Journal Article
Pinon, L. G. P.; Minichiello, L.; Klein, R.; Davies, A. M.: Timing of neuronal death in trkA, trkB and trkC mutant embryos reveals developmental changes in sensory neuron dependence on Trk signalling. Development 122 (10), pp. 3255 - 3261 (1996)
1995
Journal Article
Bergemann, A. D.; Cheng, H. J.; Brambilla, R.; Klein, R.; Flanagan, J. G.: ELF-2, a new member of the Eph ligand family, is segmentally expressed in mouse embryos in the region of the hindbrain and newly forming somites. Molecular and Cellular Biology (Washington, DC) 15 (9), pp. 4921 - 4929 (1995)
Journal Article
Brambilla, R.; Klein, R.: Telling axons where to grow: A role for Eph receptor tyrosine kinases in guidance. Molecular and Cellular Neuroscience 6 (6), pp. 487 - 495 (1995)
Journal Article
Brambilla, R.; Schnapp, A.; Casagranda, F.; Labrador, J. P.; Bergemann, A. D.; Flanagan, J. G.; Pasquale, E. B.; Klein, R.: Membrane-bound LERK2 ligand can signal through three different Eph-related receptor tyrosine kinases. The EMBO Journal 14 (13), pp. 3116 - 3126 (1995)
Journal Article
Davies, A. M.; Minichiello, L.; Klein, R.: Developmental changes in NT3 signaling via TrkA and TrkB in embryonic neurons. The EMBO Journal 14 (18), pp. 4482 - 4489 (1995)
Journal Article
Gassmann, M.; Casagranda, F.; Orioli, D.; Simon, H.; Lai, C.; Klein, R.; Lemke, G.: Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor. Nature 378 (6555), pp. 390 - 394 (1995)
Journal Article
Minichiello, L.; Piehl, F.; Vazquez, E.; Schimmang, T.; Hokfelt, T.; Represa, J.; Klein, R.: Differential effects of combined trk receptor mutations on dorsal root ganglion and inner ear sensory neurons. Development 121 (12), pp. 4067 - 4075 (1995)
Journal Article
Schimmang, T.; Minichiello, L.; Vazquez, E.; Jose, I. S.; Giraldez, F.; Klein, R.; Represa, J.: Developing inner ear sensory neurons require TrkB and TrkC receptors for innervation of their peripheral targets. Development 121 (10), pp. 3381 - 3391 (1995)
Journal Article
Tannahill, L.; Klein, R.; Schachner, M.: The neurotrophin receptors TrkA and TrkB are inhibitory for neurite outgrowth. European Journal of Neuroscience: European Neuroscience Association 7 (6), pp. 1424 - 1428 (1995)
1994
Journal Article
Klein, R.: Role of neurotrophins in mouse neuronal development. The FASEB Journal 8 (10), pp. 738 - 744 (1994)
Journal Article
Klein, R.; Silossantiago, I.; Smeyne, R. J.; Lira, S. A.; Brambilla, R.; Bryant, S.; Zhang, L.; Snider, W. D.; Barbacid, M.: Disruption of the neurotrophin-3 receptor gene trkC eliminates Ia muscle afferents and results in abnormal movements. Nature 368 (6468), pp. 249 - 251 (1994)
Journal Article
Smeyne, R. J.; Klein, R.; Schnapp, A.; Long, L. K.; Bryant, S.; Lewin, A.; Lira, S. A.; Barbacid, M.: Severe sensory and sympathetic neuropathies in mice carrying a disrupted trk/NGF receptor gene. Nature 368 (6468), pp. 246 - 249 (1994)
1993
Journal Article
Beck, K. D.; Lamballe, F.; Klein, R.; Barbacid, M.; Schauwecker, P. E.; McNeill, T. H.; Finch, C. E.; Hefti, F.; Day, J. R.: Induction of noncatalytic TrkB neurotrophin receptors during axonal sprouting in the adult hippocampus. The Journal of Neuroscience 13 (9), pp. 4001 - 4014 (1993)
Journal Article
Ip, N. Y.; Stitt, T. N.; Tapley, P.; Klein, R.; Glass, D. J.; Fandl, J.; Greene, L. A.; Barbacid, M.; Yancopoulos, G. D.: Similarities and differences in the way neurotrophins interact with the Trk receptors in neuronal and nonneuronal cells. Neuron 10 (2), pp. 137 - 149 (1993)
Journal Article
Klein, R.; Smeyne, R. J.; Wurst, W.; Long, L. K.; Auerbach, B. A.; Joyner, A. L.; Barbacid, M.: Targeted disruption of the trkB neurotrophin receptor gene results in nervous system lesions and neonatal death. Cell 75 (1), pp. 113 - 122 (1993)
Journal Article
Marsh, H. N.; Scholz, W. K.; Lamballe, F.; Klein, R.; Nanduri, V.; Barbacid, M.; Palfrey, H. C.: Signal transduction events mediated by the BDNF receptor gp 145trkB in primary hippocampal pyramidal cell culture. The Journal of Neuroscience 13 (10), pp. 4281 - 4292 (1993)
Journal Article
Steininger, T. L.; Wainer, B. H.; Klein, R.; Barbacid, M.; Palfrey, H. C.: High-affinity nerve growth factor receptor (Trk) immunoreactivity is localized in cholinergic neurons of the basal forebrain and striatum in the adult rat brain. Brain Research 612 (1-2), pp. 330 - 335 (1993)
1992
Journal Article
Klein, R.; Lamballe, F.; Bryant, S.; Barbacid, M.: The trkB tyrosine protein kinase is a receptor for neurotrophin-4. Neuron 8 (5), pp. 947 - 956 (1992)
1991
Journal Article
Barbacid, M.; Lamballe, F.; Pulido, D.; Klein, R.: The trk family of tyrosine protein kinase receptors. Biochimica et Biophysica Acta: BBA 1072 (2-3), pp. 115 - 127 (1991)
Journal Article
Cordon-Cardo, C.; Tapley, P.; Jing, S. Q.; Nanduri, V.; Orourke, E.; Lamballe, F.; Kovary, K.; Klein, R.; Jones, K. R.; Reichardt, L. F. et al.; Barbacid, M.: The trk tyrosine protein kinase mediates the mitogenic properties of nerve growth factor and neurotrophin-3. Cell 66 (1), pp. 173 - 183 (1991)
Journal Article
Klein, R.; Jing, S. Q.; Nanduri, V.; Orourke, E.; Barbacid, M.: The trk proto-oncogene encodes a receptor for nerve growth factor. Cell 65 (1), pp. 189 - 197 (1991)
Journal Article
Klein, R.; Nanduri, V.; Jing, S. Q.; Lamballe, F.; Tapley, P.; Bryant, S.; Cordon-Cardo, C.; Jones, K. R.; Reichardt, L. F.; Barbacid, M.: The trkB tyrosine protein kinase is a receptor for brain-derived neurotrophic factor and neurotrophin-3. Cell 66 (2), pp. 395 - 403 (1991)
Journal Article
Lamballe, F.; Klein, R.; Barbacid, M.: trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3. Cell 66 (5), pp. 967 - 979 (1991)
1990
Journal Article
Coulier, F.; Kumar, R.; Ernst, M.; Klein, R.; Martin-Zanca, D.; Barbacid, M.: Human trk oncogenes activated by point mutation, in-frame deletion and duplication of the tyrosine kinase domain. Molecular and Cellular Biology (Washington, DC) 10 (8), pp. 4202 - 4210 (1990)
Journal Article
Klein, R.; Conway, D.; Parada, L. F.; Barbacid, M.: The trkB tyrosine protein kinase gene codes for a second neurogenic receptor that lacks the catalytic kinase domain. Cell 61 (4), pp. 647 - 656 (1990)
Journal Article
Klein, R.; Martinzanca, D.; Barbacid, M.; Parada, L. F.: Expression of the tyrosine kinase receptor gene trkB is confined to the murine embryonic and adult nervous system. Development 109 (4), pp. 845 - 850 (1990)
1989
Journal Article
Klein, R.; Parada, L. F.; Coulier, F.; Barbacid, M.: trkB, a novel tyrosine protein kinase receptor expressed during mouse neural development. The EMBO Journal 8 (12), pp. 3701 - 3709 (1989)
1988
Journal Article
Klein, R.; Thiel, H. J.: A high-molecular-weight PDGF-like factor secreted by v-sis-transformed cells leads to growth stimulation and transformation. Oncogene Research 2 (4), pp. 311 - 324 (1988)
Journal Article
Klein, R.; Thiel, H. J.: Highly glycosylated PDGF-like molecule secreted by simian sarcoma virus - transformed cells. Virology 164 (2), pp. 403 - 410 (1988)
Journal Article
Schickedanz, J.; Philipson, L.; Ansorge, W.; Pepperkok, R.; Klein, R.; Koszinowski, U. H.: The 89,000-Mr murine cytomegalovirus immediate-early protein stimulates c-fos expression and cellular DNA synthesis. Journal of Virology 62 (9), pp. 3341 - 3347 (1988)
1985
Journal Article
Klein, R.; Bleiholder, B.; Jung, A.; Erkert, H. G.: Diurnal variation of several blood parameters in the owl monkey, Aotus trivirgatus griseimembra. Folia primatologica 45 (3-4), pp. 195 - 203 (1985)

Book Chapter (8)

2015
Book Chapter
Gaitanos, T.; Dudanova, I.; Sakkou, M.; Klein, R.; Paixao, S.: The Eph receptor family. In: Receptor tyrosine kinases: Family and subfamilies, pp. 165 - 264 (Eds. Wheeler, D. L.; Yarden, Y.). Springer International Publishing, Cham (2015)
2013
Book Chapter
Filosa, A.; Klein, R.: Ephrins and Eph receptors – Synaptogenesis and synaptic function. In: Cellular Migration and Formation of Neuronal Connections. Comprehensive Developmental Neuroscience, pp. 659 - 670 (Eds. Rubenstein, J.; Rakic, P.). Academic Press, San Diego (2013)
2011
Book Chapter
Hübener, M.; Klein, R.: Elektrisch aktiv: Funktion und Entwicklung des Gehirns. In: Zukunft Gehirn: Neue Erkenntnisse, neue Herausforderungen. Ein Report der Max-Planck-Gesellschaft, pp. 12 - 36 (Eds. Bonhoeffer, T.; Gruss, P.). C.H Beck, München (2011)
2004
Book Chapter
Klein, R.: Eph receptors. In: Handbook of Cell Signaling, Vol. 1, pp. 421 - 426 (Eds. Bradshaw, R. A.; Dennis, E. A.). Academic Press, Amsterdam, Heidelberg (2004)
2000
Book Chapter
Plück-Becklas, A.-R.; Klein, R.: Tiermodelle. In: Molekulare Medizin: Grundlagen - Pathomechanismen - Klinik, pp. 238 - 250 (Eds. Kulozik, A. E.; Hagemeier, C.; Bartram, C. R.). Walter De Gruyter, Berlin, Boston (2000)
1997
Book Chapter
Klein, R.; Bandtlow, C.: Neurotrophe Faktoren. In: Klinische Neurobiologie, pp. 39 - 59 (Eds. Herdegen, T.; Tölle, T. R.; Bähr, M.). Spektrum Akademischer Verlag, Heidelberg (1997)
1996
Book Chapter
Pasquale, E. B.; Matthews, W.; Klein, R.: LERK2 and LERK5/HTK-L. In: Human Cytokines: Handbook for Basic and Clinical Research, Vol. III (Eds. Aggarwal, B. B.; Gutterman, J. U.). Blackwell Science (1996)
1990
Book Chapter
Martin-Zanca, D.; Klein, R.; Barbacid, M.; Parada, L. F.: Expression of the trk protein tyrosine kinase receptor gene family is limited exclusively to the murine embryonic and mature nervous system. In: The avian model in developmental biology: From organism to genes (Ed. LeDouarin, N. M.). Editions du Centre National de la Recherche Scientifique, Paris (1990)

Conference Paper (1)

1992
Conference Paper
Lamballe, F.; Klein, R.; Barbacid, M.: The trk family of oncogenes and neurotrophin receptors. In: Multistage Carcinogenesis: Proceedings of the 22nd International Symposium of the Princess Takamatsu Cancer Research Fund, Tokyo, pp. 153 - 170 (Eds. Harris, C. C.; Hirohashi, S.; Ito, N.; Pitot, H. C.; Sugimura, T. et al.). Proceedings of the 22nd International Symposium of the Princess Takamatsu Cancer Research Fund, Tokyo, Tokyo, November 19, 1991 - November 21, 1991. Japan Scientific Society Press, Tokyo (1992)

Other (1)

2003
Other
Köhler, J.; Bonhoeffer, T.; Klein, R.; Kossel, A.H.: EphB2 receptors tagged with enhanced fluorescent protein to study their dynamics in living neurons, (2003)

Editorial (1)

2023
Editorial
Klein, R.; Wilkinson, D.; Herrera, E.: Friedrich Bonhoeffer (1932-2021). Neuroscience 508, pp. 1 - 2 (2023)

Review Article (1)

2021
Review Article
Klein, R.; Pasterkamp, R. J.: Recent advances in inter-cellular interactions during neural circuit assembly. (2021)
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