Publications of Tobias Derfuss

Journal Article (22)

2012
Journal Article
Krumbholz, M.; Derfuss, T.; Hohlfeld, R.; Meinl, E.: B cells and antibodies in multiple sclerosis pathogenesis and therapy. Nature Reviews Neurology 8 (11), pp. 613 - 623 (2012)
Journal Article
Ng, J. K. M.; Malotka, J.; Kawakami, N.; Derfuss, T.; Khademi, M.; Olsson, T.; Linington, C.; Odaka, M.; Tackenberg, B.; Pruess, H. et al.; Schwab, J. M.; Harms, L.; Harms, H.; Sommer, C.; Rasband, M. N.; Eshed-Eisenbach, Y.; Peles, E.; Hohlfeld, R.; Yuki, N.; Dornmair, K.; Meinl, E.: Neurofascin as a target for autoantibodies in peripheral neuropathies. Neurology 79 (23), pp. 2241 - 2248 (2012)
2011
Journal Article
Held, K.; Junker, A.; Dornmair, K.; Meinl, E.; Sinicina, I.; Brandt, T.; Theil, D.; Derfuss, T.: Expression of herpes simplex virus 1-encoded microRNAs in human trigeminal ganglia and their relation to local T-cell infiltrates. Journal of Virology 85 (19), pp. 9680 - 9685 (2011)
Journal Article
Meinl, E.; Derfuss, T.; Krumbholz, M.; Pröbstel, A. K.; Hohlfeld, R.: Humoral autoimmunity in multiple sclerosis. Journal of the Neurological Sciences 306 (1-2), pp. 180 - 182 (2011)
Journal Article
Pröbstel, A.-K.; Dornmair, K.; Bittner, R.; Sperl, P.; Jenne, D. E.; Magalhaes, S.; Villalobos, A.; Breithaupt, C.; Weissert, R.; Jacob, U. et al.; Krumbholz, M.; Kuempfel, T.; Blaschek, A.; Stark, W.; Gaertner, J.; Pohl, D.; Rostasy, K.; Weber, F.; Forne, I.; Khademi, M.; Olsson, T.; Brilot, F.; Tantsis, E.; Dale, R. C.; Wekerle, H.; Hohlfeld, R.; Banwell, B.; Bar-Or, A.; Meinl, E.; Derfuss, T.: Antibodies to MOG are transient in childhood acute disseminated encephalomyelitis. Neurology 77 (6), pp. 580 - 588 (2011)
2010
Journal Article
Derfuss, T.; Linington, C.; Hohlfeld, R.; Meinl, E.: Axo-glial antigens as targets in multiple sclerosis: implications for axonal and grey matter injury. Journal of Molecular Medicine 88 (8), pp. 753 - 761 (2010)
Journal Article
Meinl, E.; Derfuss, T.; Linington, C.: Identifying targets for autoantibodies in CNS inflammation: Strategies and achievements. Clinical and Experimental Neuroimmunology 1 (2), pp. 47 - 60 (2010)
2009
Journal Article
Derfuss, T.; Parikh, K.; Velhin, S.; Braun, M.; Mathey, E.; Krumbholz, M.; Kümpfel, T.; Moldenhauer, A.; Rader, C.; Sonderegger, P. et al.; Pöllmann, W.; Tiefenthaller, C.; Bauer, J.; Lassmann, H.; Wekerle, H.; Karagogeos, D.; Hohlfeld, R.; Linington, C.; Meinl, E.: Contactin-2/TAG-1-directed autoimmunity is identified in multiple sclerosis patients and mediates gray matter pathology in animals. Proceedings of the National Academy of Sciences of the United States of America 106 (20), pp. 8302 - 8307 (2009)
2008
Journal Article
Derfuss, T.; Direskeneli, G. S.; Hohlfeld, R.; Meinl, E.: Autoantigen- und erregerspezifische T- und B-Zellreaktionen bei multipler Sklerose: „Eine unendliche Geschichte”? Aktuelle Neurologie 35 (7), pp. 345 - 355 (2008)
Journal Article
Krumbholz, M.; Faber, H.; Steinmeyer, F.; Hoffmann, L. A.; Kümpfel, T.; Pellkofer, H.; Derfuss, T.; Ionescu, C.; Starck, M.; Hafner, C. et al.; Hohlfeld, R.; Meinl, E.: Interferon-beta increases BAFF levels in multiple sclerosis: implications for B cell autoimmunity. Brain 131, pp. 1455 - 1463 (2008)
Journal Article
Meinl, E.; Krumbholz, M.; Derfuss, T.; Junker, A.; Hohlfeld, R.: Compartmentalization of inflammation in the CNS: A major mechanism driving progressive multiple sclerosis. Journal of Neurological Sciences 274 (1-2), pp. 42 - 44 (2008)
Journal Article
Theil, D. J.; Libbey, J. E.; Rodriguez, F.; Whitton, J. L.; Tsunoda, I.; Derfuss, T.; Fujinami, R. S.: Targeting myelin proteolipid protein to the MHC class I pathway by ubiquitination modulates the course of experimental autoimmune encephalomyelitis. Journal of Neuroimmunology 204 (1-2), pp. 92 - 100 (2008)
2007
Journal Article
Derfuss, T.; Segerer, S.; Herberger, S.; Sinicina, I.; Hufner, K.; Ebelt, K.; Knaus, H. G.; Steiner, I.; Meinl, E.; Dornmair, K. et al.; Arbusow, V.; Strupp, M.; Brandt, T.; Theil, D.: Presence of HSV-1 immediate early genes and clonally expanded T-cells with a memory effector phenotype in human trigeminal ganglia. Brain Pathology 17 (4), pp. 389 - 398 (2007)
Journal Article
Hüfner, K.; Arbusow, V.; Himmelein, S.; Derfuss, T.; Sinicina, I.; Strupp, M.; Brandt, T.; Theil, D.: The prevalence of human herpesvirus 6 in human sensory ganglia and its co-occurrence with alpha-herpesvirus. Journal of Neurovirology 13 (5), pp. 462 - 467 (2007)
Journal Article
Krumbholz, M.; Theil, D.; Steinmeyer, F.; Cepok, S.; Hemmer, B.; Hofbauer, M.; Farina, C.; Derfuss, T.; Junker, A.; Arzberger, T. et al.; Sinicina, I.; Hartle, C.; Newcombe, J.; Hohlfeld, R.; Meinl, E.: CCL19 is constitutively expressed in the CNS, up-regulated in neuroinflammation, active and also inactive multiple sclerosis lesions. Journal of Neuroimmunology 190 (1-2), pp. 72 - 79 (2007)
Journal Article
Mathey, E. K.; Derfuss, T.; Storch, M. K.; Williams, K. R.; Hales, K.; Woolley, D. R.; Al-Hayani, A.; Davies, S. N.; Rasband, M. N.; Olsson, T. et al.; Moldenhauer, A.; Velhin, S.; Hohlfeld, R.; Meinl, E.; Linington, C.: Neurofascin as a novel target for autoantibody-mediated axonal injury. Journal of Experimental Medicine 204 (10), pp. 2363 - 2372 (2007)
2006
Journal Article
Krumbholz, M.; Theil, D.; Cepok, S.; Hemmer, B.; Kivisakk, P.; Ransohoff, R. M.; Hofbauer, M.; Farina, C.; Derfuss, T.; Hartle, C. et al.; Newcombe, J.; Hohlfeld, R.; Meinl, E.: Chemokines in multiple sclerosis: CXCL12 and CXCL13 up-regulation is differentially linked to CNS immune cell recruitment. Brain 129, pp. 200 - 211 (2006)
2005
Journal Article
Derfuss, T.; Hohlfeld, R.; Meinl, E.: Intrathecal antibody (IgG) production against human herpesvirus type 6 occurs in about 20% of multiple sclerosis patients and might be linked to a polyspecific B-cell response. Journal of Neurology 252 (8), pp. 968 - 971 (2005)
Journal Article
Krumbholz, M.; Theil, D.; Derfuss, T.; Rosenwald, A.; Schrader, F.; Monoranu, C. M.; Kalled, S. L.; Hess, D. M.; Serafini, B.; Aloisi, F. et al.; Wekerle, H.; Hohlfeld, R.; Meinl, E.: BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma. Journal of Experimental Medicine 201 (2), pp. 195 - 200 (2005)
Journal Article
Vargas-Leal, V.; Bruno, R.; Derfuss, T.; Krumbholz, M.; Hohlfeld, R.; Meinl, E.: Expression and function of glial cell line-derived neurotrophic factor (GDNF) family ligands and their receptors on human immune cells. Journal of Immunology 175 (4), pp. 2301 - 2308 (2005)
2003
Journal Article
Theil, D.; Derfuss, T.; Paripovic, I.; Herberger, S.; Meinl, E.; Schueler, O.; Strupp, M.; Arbusow, V.; Brandt, T.: Latent herpesvirus infection in human trigeminal ganglia causes chronic immune response. American Journal of Pathology 163 (6), pp. 2179 - 2184 (2003)
2001
Journal Article
Meinl, E.; Derfuss, T.; Pirzer, R.; Blank, N.; Lengenfelder, D.; Blancher, A.; Le Deist, F.; Fleckenstein, B.; Hivroz, C.: Herpesvirus saimiri replaces ZAP-70 for CD3- and CD2-mediated T cell activation. The Journal of Biological Chemistry 276 (40), pp. 36902 - 36908 (2001)

Book Chapter (2)

2009
Book Chapter
Derfuss, T.; Arbusow, V.; Strupp, M.; Brandt, T.; Theil, D.: The presence of lytic HSV-1 transcripts and clonally expanded T cells with a memory effector phenotype in human sensory ganglia. In: BASIC AND CLINICAL ASPECTS OF VERTIGO AND DIZZINESS, Vol. 1164, pp. 300 - 304 (Eds. Strupp, M.; Büttner, U.; Cohen, B.). BLACKWELL PUBLISHING, OXFORD (2009)
2002
Book Chapter
Derfuss, T.; Meinl, E.: Herpesviral proteins regulating apoptosis. In: VIRAL PROTEINS COUNTERACTING HOST DEFENSES, pp. 257 - 272. SPRINGER-VERLAG BERLIN, BERLIN (2002)
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