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BEGIN:VEVENT
DTSTAMP:20260429T214621Z
UID:https://www.bi.mpg.de/events/44934/2588681
DTSTART:20260609T090000Z
DTEND:20260609T100000Z
CLASS:PUBLIC
CREATED:20260227T103445Z
DESCRIPTION: The intrinsic organization underlying the central cognitive ro
 le of the prefrontal cortex (PFC)is poorly understood. We approach organiz
 ation by profiling the activity and spatial location of &gt\; 23\,000 neur
 ons recorded in awake mice. High-resolution activity maps of the PFC do no
 t align with cytoarchitecturally defined subregions. Instead\, spontaneous
  activity and tuning to choice during a behavioral task were both related 
 to intra-PFC hierarchy\, suggesting that connectivity\, rather than cytoar
 chitecture\, shapes the PFC’s activity landscape. Low-rate\, regular spo
 ntaneous firing was a hallmark of the PFC and of high hierarchy. Surprisin
 gly\, choice tuning is over-represented in units displaying high spontaneo
 us firing rates\, linking connectivity-based hierarchy to distinct functio
 nal properties\, in separate neuronal populations. Our data-driven approac
 h provides a scalable roadmap to obtain an integrated view of activity\, s
 tructure\, and function in the brain\, opening new avenues to explore func
 tional organizations using single neuron activities across species and bra
 in regions.\nVortragender: Pierre Le Merre
LAST-MODIFIED:20260227T103636Z
LOCATION:MPI BI Martinsried\, Raum: NQ 105 and streamed to MPI BI Seewiesen
 \, house 5\, seminar room 0.23
ORGANIZER;CN=Felix Jung:mailto:
SUMMARY:A Prefrontal Cortex Map based on Single-Neuron Activity
URL;VALUE=URI:https://www.bi.mpg.de/events/44934/2588681
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